Tang Hu, Wei Lan, Yang Zijie, Zhu Yue, Zhang Yan, Zheng Chenli, Yuan Xiaohong, Chen Jiachun, Zhao Jin
School of Public Health, Shanxi Medical University, Taiyuan City, Shanxi Province, China.
Sexually Transmitted Disease & Acquired Immunodeficiency Syndrome Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
China CDC Wkly. 2025 Jul 25;7(30):997-1003. doi: 10.46234/ccdcw2025.168.
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Partner tracing (PT) represents an established public health strategy for identifying undiagnosed individuals with human immunodeficiency virus (HIV) infection and contributes to controlling sustained HIV transmission.
WHAT IS ADDED BY THIS REPORT?: Partner tracing among newly diagnosed HIV-infected men who have sex with men (MSM) demonstrates effectiveness in identifying undiagnosed infected individuals, with regular sexual partners showing higher likelihood of HIV-positive detection. However, phylogenetic analysis revealed that only a small proportion of epidemiologically linked pairs exhibited genetic linkage.
WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Sustained implementation and broader application of partner tracing may serve a critical role in HIV epidemic control by facilitating early identification of undiagnosed infections and interrupting potential transmission chains. Integrating partner tracing with phylogenetic analysis enhances the capacity to distinguish actual transmission chains from coincidental behavioral associations, thereby improving transmission linkage identification accuracy and informing more targeted intervention strategies.
性伴追踪(PT)是一种既定的公共卫生策略,用于识别未被诊断出感染人类免疫缺陷病毒(HIV)的个体,并有助于控制HIV的持续传播。
在新诊断出感染HIV的男男性行为者(MSM)中进行性伴追踪,在识别未被诊断出的感染个体方面显示出有效性,与固定性伴发生性行为者被检测出HIV阳性的可能性更高。然而,系统发育分析显示,在流行病学关联的配对中,只有一小部分呈现出基因连锁关系。
持续实施并更广泛地应用性伴追踪,可能通过促进未被诊断出的感染的早期识别以及中断潜在传播链,在HIV疫情控制中发挥关键作用。将性伴追踪与系统发育分析相结合,可提高区分实际传播链与偶然行为关联的能力,从而提高传播关联识别的准确性,并为更具针对性的干预策略提供依据。