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Single-cell RNA sequencing identifies a peripheral monocyte subpopulation and its interaction with atrial macrophages via the CCL3-CCR1 axis during atrial remodeling.

作者信息

Xiong Chenlu, Wang Yihan, Liao Wenkai, Ma Xuemei, Xie Fei, Chen Mulei

机构信息

College of Chemistry and Life Science, Beijing University of Technology, Beijing, 100124, China.

School of The Third Clinical Medical College, Capital Medical University, Beijing, 100020, China.

出版信息

Sci China Life Sci. 2025 Aug 15. doi: 10.1007/s11427-025-3023-9.

DOI:10.1007/s11427-025-3023-9
PMID:40833709
Abstract
摘要

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本文引用的文献

1
Atrial remodelling and atrial fibrillation self-sustaining: the role of circulating circDGCR8.心房重塑与心房颤动的自我维持：循环circDGCR8的作用
Cardiovasc Res. 2025 Jul 8;121(7):1036-1051. doi: 10.1093/cvr/cvaf060.
2
Recruited macrophages elicit atrial fibrillation.募集的巨噬细胞引发心房颤动。
Science. 2023 Jul 14;381(6654):231-239. doi: 10.1126/science.abq3061. Epub 2023 Jul 13.
3
Immune remodeling and atrial fibrillation.免疫重塑与心房颤动
Front Physiol. 2022 Jul 22;13:927221. doi: 10.3389/fphys.2022.927221. eCollection 2022.
4
IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation.IFNγ 和 GM-CSF 控制神经炎症期间单核细胞向吞噬细胞过渡中的互补分化程序。
Nat Immunol. 2022 Feb;23(2):217-228. doi: 10.1038/s41590-021-01117-7. Epub 2022 Jan 31.
5
Global epidemiology of atrial fibrillation: An increasing epidemic and public health challenge.心房颤动的全球流行病学：日益严重的流行趋势及公共卫生挑战。
Int J Stroke. 2021 Feb;16(2):217-221. doi: 10.1177/1747493019897870. Epub 2020 Jan 19.
6
Atrial fibrillation and cardiac fibrosis.心房颤动与心脏纤维化。
Eur Heart J. 2020 Mar 7;41(10):1123-1131. doi: 10.1093/eurheartj/ehz786.
7
Crosstalk between fibroblasts and inflammatory cells.成纤维细胞与炎症细胞间的串扰。
Cardiovasc Res. 2014 May 1;102(2):258-69. doi: 10.1093/cvr/cvu062. Epub 2014 Apr 11.
8
Cardiac ion channels and mechanisms for protection against atrial fibrillation.心脏离子通道与抗心房颤动的机制。
Rev Physiol Biochem Pharmacol. 2012;162:1-58. doi: 10.1007/112_2011_3.
9
Patterns of baseline autonomic nerve activity and the development of pacing-induced sustained atrial fibrillation.基础自主神经活动模式与起搏诱导持续性心房颤动的发展。
Heart Rhythm. 2011 Apr;8(4):583-9. doi: 10.1016/j.hrthm.2010.11.040. Epub 2010 Nov 29.
10
Electrical, contractile and structural remodeling during atrial fibrillation.心房颤动期间的电重构、收缩重构和结构重构。
Cardiovasc Res. 2002 May;54(2):230-46. doi: 10.1016/s0008-6363(02)00258-4.