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两只犬自然发生的传染性性病肿瘤相关的病毒样颗粒:初步报告

Viral-like particles associated with naturally occurring transmissible venereal tumor in two dogs: preliminary report.

作者信息

Amber E I, Isitor G N, Adeyanju J B

出版信息

Am J Vet Res. 1985 Dec;46(12):2613-5.

PMID:4083601
Abstract

Naturally occurring canine transmissible venereal tumors in 2 dogs were examined ultrastructurally, using a transmission electron microscope. Typical nondegenerating cells of various shapes with normal cytoplasmic organellae were seen. Degenerating and necrotic cells characterized by loss of normal organellae with vacuolations of the cytoplasm were in all sections studied. Icosahedral electron-dense particles (22 nm diameter) were in the degenerating and necrotic cells. The uniqueness of this finding is not known. The shape and size of the particles indicate that there may be viral involvement.

摘要

使用透射电子显微镜对2只犬自然发生的犬传染性性病肿瘤进行了超微结构检查。可见具有正常细胞质细胞器的各种形状的典型未退化细胞。在所有研究的切片中均可见到以正常细胞器丧失和细胞质空泡化为特征的退化和坏死细胞。二十面体电子致密颗粒(直径22纳米)存在于退化和坏死细胞中。这一发现的独特性尚不清楚。颗粒的形状和大小表明可能有病毒参与。

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