Chan Nicholas J, Lentz Sarah, Gurr Paul A, Tan Shereen, Schultebeyring Mona, Rosenfeldt Sabine, Schenk Anna, Scheibel Thomas, Qiao Greg G
Polymer Science Group, Department of Chemical Engineering University of Melbourne Parkville, Melbourne Victoria 3010 Australia.
Lehrstuhl Biomaterialien Universität Bayreuth Prof.-Rüdiger-Bormann-Str. 1 D-95447 Bayreuth Germany.
Small Sci. 2025 May 26;5(8):2500115. doi: 10.1002/smsc.202500115. eCollection 2025 Aug.
In natural silks, -sheet crystals are embedded within an amorphous matrix resulting in polypeptide-based nanocomposites. These -sheet crystals contribute to the subsequent high strength and toughness of spider silk. Consequently, imitation and mimicry of such concepts utilizing polypeptides provide a pathway toward putatively achieving similar properties. Herein, the introduction of poly(l-valine) (PVal) -sheet nanocrystals into different fibers is investigated. Analysis of micro- and nanoscale features shows that polyvaline -sheets could be implemented into fibers made from different polymer classes, ranging from standard polymers (polycaprolactone (PCL), Nylon 6) to biopolymers like cellulose and recombinant spider silk. The in situ implementation of PVal during wet-spinning leads to a significant change in the resulting mechanical properties, depending on the polymer used.
在天然丝中，β-片层晶体嵌入无定形基质中，形成基于多肽的纳米复合材料。这些β-片层晶体有助于蜘蛛丝随后具备高强度和韧性。因此，利用多肽模仿和模拟此类概念为假定实现类似性能提供了一条途径。在此，研究了将聚（L-缬氨酸）（PVal）β-片层纳米晶体引入不同纤维的情况。对微观和纳米尺度特征的分析表明，聚缬氨酸β-片层可以被应用到由不同聚合物类别制成的纤维中，从标准聚合物（聚己内酯（PCL）、尼龙6）到纤维素和重组蜘蛛丝等生物聚合物。在湿法纺丝过程中原位引入PVal会导致所得机械性能发生显著变化，这取决于所使用的聚合物。
