Li Zhenyu, Zhao Zhiguang, Zhang Geng, Wang He, Zhang Bo, Zhang Wei
Department of Urology, Tangdu Hospital, Air Force Military Medical University, Xi'an, China.
Front Reprod Health. 2025 Aug 5;7:1555597. doi: 10.3389/frph.2025.1555597. eCollection 2025.
This study aims to explore the clinical efficacy and safety of a urethroplasty technique for fossa navicularis (FN) strictures using a transurethral annular inlay oral mucosa graft.
A retrospective analysis was conducted on clinical data from patients with urethral meatus and navicular fossa stricture who underwent transurethral reconstruction using annular inlay oral mucosa graft urethroplasty in Tangdu Hospital from July 2021 to October 2024. Operation success was defined as the ability to pass the F24 urethral probe, and the secondary outcome is the urinary flow rate and patient satisfaction at 1, 3, 6, and 12 months.
All 12 patients successfully completed the surgery. The average age was 56.8 ± 6.8 years, and the average length of urethral stricture was 1.6 ± 0.2 cm. Three patients had a history of transurethral endoscopic surgery, eight had penile lichen sclerosus (LS), and one had no obvious causes. Over a median follow-up of 19 months, the average maximum urinary flow rate was 21.2 ± 3.2 ml/s at 3 months, and the average maximum urinary flow rate was 19.5 ± 4.2 ml/s at 12 months. One patient experienced urine pain with a thin stream and spraying urination after 3 months. Physical examination of the urethral meatus opening scar was found, and the symptoms disappeared after urethral incision. The follow-up survey of sexual life after 1 year showed that seven patients (58.3%) had successful life within 1 year compared with two patients (16.7%) before surgery. There were no cases of erectile dysfunction and poor wound healing. The patients were either very satisfied (75%) or satisfied (25%) with the operation. All patients would recommend urethroplasty to others.
Transurethral annular inlay oral mucosa urethroplasty for urethral meatus and navicular fossa stricture reconstruction is a safe, feasible, and effective surgical method, cosmetic effect on the penile head. This technique has advantages in improving sexual function and better penile head cosmesis.
本研究旨在探讨经尿道环形镶嵌口腔黏膜移植治疗舟状窝（FN）狭窄的尿道成形术的临床疗效和安全性。
对2021年7月至2024年10月在唐都医院接受经尿道环形镶嵌口腔黏膜移植尿道成形术治疗尿道口及舟状窝狭窄患者的临床资料进行回顾性分析。手术成功定义为能够通过F24尿道探子，次要结局指标为术后1、3、6和12个月时的尿流率及患者满意度。
12例患者均成功完成手术。平均年龄为56.8±6.8岁，尿道狭窄平均长度为1.6±0.2cm。3例有经尿道内镜手术史，8例有阴茎硬化性苔藓（LS），1例病因不明。中位随访19个月，3个月时平均最大尿流率为21.2±3.2ml/s，12个月时平均最大尿流率为19.5±4.2ml/s。1例患者术后3个月出现尿痛、尿线细及尿流喷洒现象。检查发现尿道口瘢痕，经尿道切开后症状消失。术后1年性生活随访调查显示，7例患者（58.3%）术后1年内性生活成功，术前为2例（16.7%）。无勃起功能障碍及伤口愈合不良病例。患者对手术非常满意（75%）或满意（25%）。所有患者均会向他人推荐该尿道成形术。
经尿道环形镶嵌口腔黏膜尿道成形术用于尿道口及舟状窝狭窄重建是一种安全、可行且有效的手术方法，对阴茎头有美容效果。该技术在改善性功能及阴茎头美容方面具有优势。
