Goshen J, Wexler M R, Peled I J
Ann Plast Surg. 1985 Nov;15(5):431-5. doi: 10.1097/00000637-198511000-00010.
Two alpha blocking agents, phenoxybenzamine and phentolamine, were tested to see if their use improved skin flap survival in rats. The agents were used in two ways: in local injections and topical applications. The results showed an increased duration of flap viability with both modalities, but the topical application was the most effective.
测试了两种α阻滞剂——酚苄明和酚妥拉明,以观察它们的使用是否能提高大鼠皮瓣的存活率。这两种药物通过两种方式使用:局部注射和局部应用。结果显示,两种方式都能延长皮瓣存活时间,但局部应用最为有效。