Jia Xiu-Ping, Lou Qian-Xing, Chen Xiao-Zhen, Zhang Yun-Zhen
Department of Anesthesiology, Yiwu Central Hospital, Yiwu 322000, Zhejiang Province, China.
Department of Anesthesiology, Hangzhou Women's Hospital (Hangzhou Maternity and Child Health Care Hospital, Hangzhou First People's Hospital Qianjiang New City Campus), Hangzhou 310008, Zhejiang Province, China.
World J Psychiatry. 2025 Aug 19;15(8):105770. doi: 10.5498/wjp.v15.i8.105770.
Evaluating the relationship between sleep quality and depressive symptoms after laparoscopic hysterectomy under general anesthesia can help improve postoperative depressive symptoms.
To evaluate the correlation between sleep quality and depression symptoms in patients after laparoscopic hysterectomy under general anesthesia and explore factors associated with postoperative sleep disturbances and depression.
This retrospective case-control study included 102 females who underwent laparoscopic hysterectomy under general anesthesia at our hospital between January 2022 and June 2024, excluding those with severe cardiovascular/cerebrovascular disease, liver/kidney dysfunction, or other underlying conditions. Sleep quality and depressive symptoms were evaluated preoperatively and at 1-week, 1-month, and 3-months postoperatively using the Pittsburgh Sleep Quality Index (PSQI) and the Hamilton Depression Rating Scale (HAMD). Physiological indicators (heart rate, blood pressure, and oxygen saturation) and laboratory parameters were monitored. Pearson correlation and logistic regression analyses were performed to examine the association between sleep quality and depressive symptoms.
Mean age of participants was (52.30 ± 8.39) years, with a body mass index of (23.56 ± 2.79) kg/m². Preoperative comorbidities included hypertension (25.49%), diabetes (14.71%), and heart disease (9.80%). Patients with poor preoperative sleep quality (higher PSQI scores) exhibited significantly more severe depressive symptoms ( < 0.05). Postoperative PSQI scores improved at 1-week, 1-month, and 3-months compared to baseline ( < 0.05). HAMD scores decreased at 1-week and 1-month postoperatively but returned to near preoperative levels at 3-months. Physiological indicators remained within normal ranges, and the postoperative complication rate was < 5%. Logistic regression showed that poor postoperative sleep quality was an independent predictor of depressive symptoms (odds ratio = 1.64, 95%CI: 1.22-2.20, < 0.05).
Sleep quality was significantly correlated with depressive symptoms after laparoscopic hysterectomy under general anesthesia. Patients with poor postoperative sleep quality were more prone to depression. Early interventions for sleep disturbances are potentially beneficial for mitigating depression and improve mental health.
评估全身麻醉下腹腔镜子宫切除术后睡眠质量与抑郁症状之间的关系有助于改善术后抑郁症状。
评估全身麻醉下腹腔镜子宫切除术后患者睡眠质量与抑郁症状之间的相关性，并探讨与术后睡眠障碍和抑郁相关的因素。
这项回顾性病例对照研究纳入了2022年1月至2024年6月期间在我院接受全身麻醉下腹腔镜子宫切除术的102名女性，排除患有严重心血管/脑血管疾病、肝/肾功能不全或其他基础疾病的患者。术前以及术后1周、1个月和3个月使用匹兹堡睡眠质量指数（PSQI）和汉密尔顿抑郁评定量表（HAMD）评估睡眠质量和抑郁症状。监测生理指标（心率、血压和血氧饱和度）和实验室参数。进行Pearson相关性分析和逻辑回归分析以检验睡眠质量与抑郁症状之间的关联。
参与者的平均年龄为（52.30±8.39）岁，体重指数为（23.56±2.79）kg/m²。术前合并症包括高血压（25.49%）、糖尿病（14.71%）和心脏病（9.80%）。术前睡眠质量差（PSQI评分较高）的患者表现出明显更严重的抑郁症状（<0.05）。与基线相比，术后1周、1个月和3个月的PSQI评分有所改善（<0.05）。术后1周和1个月时HAMD评分下降，但在3个月时恢复到接近术前水平。生理指标保持在正常范围内，术后并发症发生率<5%。逻辑回归显示，术后睡眠质量差是抑郁症状的独立预测因素（优势比=1.64，95%CI：1.22 - 2.20，<0.05）。
全身麻醉下腹腔镜子宫切除术后睡眠质量与抑郁症状显著相关。术后睡眠质量差的患者更容易出现抑郁。对睡眠障碍进行早期干预可能有助于减轻抑郁并改善心理健康。
