Khalaf-Adeli Elham, Tobeyani Fatemeh
Department of Hematology, Faculty of Paramedical Sciences, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.
Asian J Transfus Sci. 2025 Jan-Jun;19(1):130-137. doi: 10.4103/ajts.ajts_18_23. Epub 2025 Jun 30.
Limitation of standard coagulation tests in early detection of coagulopathy leads to empirical decision-making for the management of the coagulopathy, which in many cases is accompanied by improper transfusion. Some studies have investigated the role of rotational thromboelastometry (ROTEM) in reducing the need for blood products in different clinical conditions, which have been associated with different results. Whether ROTEM as a point of care test reduces the need for transfusion in all clinical settings is still a question. A brief introduction of methodology of ROTEM and its role in patient blood management (PBM) approach is explored in this review. Search was performed to find literature describing ROTEM applied for decrease in transfusion requirements. Specific search terms were "Thromboelastometry," "ROTEM," "Cardiac surgical procedures," "Trauma," "wounds and injuries" "Liver transplantation," "obstetric" "Transfusion," and "PBM." we reached to 75 publications for this review after application of our search strategy. The number of publications in the field of obstetric was insufficient for review and conclusion. The available evidence supports the helpfulness of ROTEM test in reducing the need for blood transfusions in surgery or trauma. However, it is need to further investigation to evaluate the benefit and efficacy of ROTEM in other medical conditions such as obstetric hemorrhage.
标准凝血试验在早期检测凝血功能障碍方面存在局限性,这导致在处理凝血功能障碍时只能凭经验做出决策,而在许多情况下,这种决策伴随着不恰当的输血。一些研究调查了旋转血栓弹力图(ROTEM)在不同临床情况下减少血液制品需求方面的作用,这些研究结果各不相同。ROTEM作为一种床旁检测方法是否能在所有临床环境中减少输血需求仍是一个问题。本综述探讨了ROTEM的方法学及其在患者血液管理(PBM)方法中的作用。通过检索来查找描述ROTEM用于减少输血需求的文献。具体检索词为“血栓弹力图”“ROTEM”“心脏外科手术”“创伤”“伤口和损伤”“肝移植”“产科”“输血”和“PBM”。在应用检索策略后,我们找到了75篇用于本综述的出版物。产科领域的出版物数量不足以进行综述和得出结论。现有证据支持ROTEM检测在减少手术或创伤中输血需求方面的有效性。然而,需要进一步研究以评估ROTEM在其他医疗状况(如产科出血)中的益处和效果。