Mironov A A, Mironov V A, Rekhter M D
Arkh Anat Gistol Embriol. 1985 Oct;89(10):54-60.
In the experiments performed on 53 Kioto-Wistar normotensive rats, the reaction of endothelial cells of the abdominal aorta has been analysed in response to the lesion by freezing or by hypoosmotic effect. At first the deendothelized surface is covered with flatten thrombocytes, and then the continuity of the endothelium is restorted as a result of migration and proliferation of endotheliocytes. This is accompanied with a reconstruction of their cytoskeleton (structurization and redistribution). The immature endothelium is characterized by an increased numerical density of strongly elongated endothelial cells, decreased resistency to collagenase effect and a great adhesiveness to blood leucocytes. No essential differences in the reaction of endotheliocytes are revealed in dependence of deendothelization means.
在对53只京都-威斯塔正常血压大鼠进行的实验中，分析了腹主动脉内皮细胞对冷冻或低渗效应所致损伤的反应。起初，去内皮表面覆盖着扁平的血小板，随后内皮细胞的迁移和增殖使内皮的连续性得以恢复。这伴随着细胞骨架的重建（结构化和重新分布）。未成熟的内皮细胞表现为高度伸长的内皮细胞数量密度增加、对胶原酶作用的抵抗力降低以及对血液白细胞的黏附性增强。未发现内皮细胞反应因去内皮方法的不同而有本质差异。
