[Changes in the endothelium of the aorta of the rat during regeneration (according to the results of scanning electron microscopy)].

In the experiments performed on 53 Kioto-Wistar normotensive rats, the reaction of endothelial cells of the abdominal aorta has been analysed in response to the lesion by freezing or by hypoosmotic effect. At first the deendothelized surface is covered with flatten thrombocytes, and then the continuity of the endothelium is restorted as a result of migration and proliferation of endotheliocytes. This is accompanied with a reconstruction of their cytoskeleton (structurization and redistribution). The immature endothelium is characterized by an increased numerical density of strongly elongated endothelial cells, decreased resistency to collagenase effect and a great adhesiveness to blood leucocytes. No essential differences in the reaction of endotheliocytes are revealed in dependence of deendothelization means.