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胆囊穿孔继发胆囊支气管瘘的两阶段治疗:一例报告

Two-stage treatment of cholecystobronchial fistula secondary to gallbladder perforation: a case report.

作者信息

Li Wenbo, Li Liang, Jiang You, Liu Jiayang

机构信息

Department of General Surgery, The Second People's Hospital of Hefei (Hefei Hospital Affiliated to Anhui Medical University), Hefei, 230011, Anhui Province, People's Republic of China.

出版信息

J Med Case Rep. 2025 Aug 21;19(1):422. doi: 10.1186/s13256-025-05489-4.

Abstract

BACKGROUND

Gallbladder perforation is a serious complication of acute cholecystitis. Among its rarest manifestations, cholecystobronchial fistula represents an exceptionally uncommon form of type III perforation and is frequently misdiagnosed due to its nonspecific presentation. A 67-year-old Chinese (East Asian) male presented with a chief complaint of cough and hemoptysis. His medical history was significant for nephrotic syndrome, for which he had been receiving long-term corticosteroid therapy. Imaging demonstrated cholelithiasis, a cholecystobronchial fistula, and a right-sided lung abscess. A staged treatment approach was implemented. Stage I involved ultrasound-guided percutaneous transhepatic gallbladder drainage for infection control. Following clinical stabilization, stage II consisted of laparoscopic cholecystectomy. Intraoperative findings confirmed spontaneous closure of the fistula. The patient achieved an uneventful recovery and remained recurrence-free during follow-up.

CONCLUSION

Cholecystobronchial fistula typically results from chronic gallbladder inflammation. Prolonged corticosteroid use may obscure clinical manifestations, potentially delaying diagnosis. Contrast-enhanced computed tomography is essential for fistula identification, supplemented by bronchoscopic bilirubin or microbiological analysis. A staged minimally invasive approach enhances both safety and therapeutic efficacy. This report underscores the critical importance of multidisciplinary collaboration, precise imaging, and individualized surgical planning in the management of rare biliary fistulas.

摘要

背景

胆囊穿孔是急性胆囊炎的一种严重并发症。在其最罕见的表现中,胆囊支气管瘘是III型穿孔的一种异常罕见形式,因其表现不具特异性,常被误诊。一名67岁的中国(东亚)男性,主要症状为咳嗽和咯血。他有肾病综合征病史,长期接受皮质类固醇治疗。影像学检查显示有胆结石、胆囊支气管瘘和右侧肺脓肿。实施了分期治疗方法。第一阶段包括超声引导下经皮经肝胆囊引流以控制感染。临床稳定后,第二阶段为腹腔镜胆囊切除术。术中发现瘘口自发闭合。患者恢复顺利,随访期间无复发。

结论

胆囊支气管瘘通常由慢性胆囊炎症引起。长期使用皮质类固醇可能掩盖临床表现,从而可能延迟诊断。对比增强计算机断层扫描对于瘘口识别至关重要,辅以支气管镜胆红素或微生物分析。分期微创方法可提高安全性和治疗效果。本报告强调了多学科协作、精确成像和个体化手术规划在罕见胆瘘管理中的至关重要性。

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