Zhou Peng, Zhu Jiandong, Sun Liang, Lu Jinxin, Ji Chengyuan, Yu Zhengquan, Wu Jiang, Bu Jiyuan
Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu Province, China.
BMC Surg. 2025 Aug 21;25(1):379. doi: 10.1186/s12893-025-03138-7.
The aim of this study was to retrospectively analyze the clinical data of 24 patients with small vestibular schwannomas, explore the surgical outcomes, and summarize the surgical experience.
Patients with small vestibular schwannomas who underwent surgery between January 2019 and December 2022 at the Department of Neurosurgery of the First Affiliated Hospital of Soochow University were included. Clinical data from all patients were collected and analyzed.
Total tumor resection was achieved in all patients. Microscopic surgery alone was sufficient for complete resection in 7 patients, while the remaining 17 patients required combined microscopic and endoscopic approaches for complete removal. At the final follow-up, 16 patients maintained preoperative facial nerve function, 6 patients experienced improvement, while 2 patients experienced deterioration. And there were 13 patients maintained preoperative hearing function, 9 patients experienced improvement, while 2 patients experienced deterioration. Compared with microscopic resection alone, there was no significant difference in the Facial nerve function and Hearing function of patients underwent microscopic and endoscopic resection. During the follow-up period, all patients showed favorable prognosis without disease progression.
Compared with microscopic surgery, the microscopic with endoscopic surgery for small vestibular schwannomas lead to the better results in the degree of tumor resection, with no difference in functional protection.
本研究旨在回顾性分析24例小听神经瘤患者的临床资料,探讨手术效果,并总结手术经验。
纳入2019年1月至2022年12月在苏州大学第一附属医院神经外科接受手术的小听神经瘤患者。收集并分析所有患者的临床资料。
所有患者均实现肿瘤全切除。仅显微手术即可完全切除肿瘤的患者有7例,其余17例患者需要显微手术联合内镜手术才能完全切除。末次随访时,16例患者保留术前面神经功能,6例患者面神经功能改善,2例患者面神经功能恶化。13例患者保留术前听力功能,9例患者听力改善,2例患者听力恶化。与单纯显微切除术相比,接受显微手术联合内镜切除术患者的面神经功能和听力功能差异无统计学意义。随访期间,所有患者预后良好,无疾病进展。
与显微手术相比,显微手术联合内镜手术治疗小听神经瘤在肿瘤切除程度上效果更好,在功能保护方面无差异。