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一直以来,使用机械瓣膜进行主动脉瓣置换是正确的选择吗?伴有复发性主动脉瓣反流的科根综合征:一个手术决策不断演变的病例。

Was an aortic valve replacement with a mechanical valve the right option all along? Cogan's syndrome with recurrent aortic regurgitation: a case of evolving surgical decisions.

作者信息

Gad Maram, Faiq Lanya, Arifagic Emma, Kamougeros Alex, Ioannou Stelios, Shiakos George, Tzanavaros Ioannis

机构信息

European University Cyprus, School of Medicine, 6 Diogenous Street, Nicosia, Engomi 2404, Cyprus.

Apollonion Private Hospital, Cardiac Innovation Center, Nicosia, Cyprus.

出版信息

Oxf Med Case Reports. 2025 Aug 20;2025(8):omaf143. doi: 10.1093/omcr/omaf143. eCollection 2025 Aug.

Abstract

Cogan Syndrome (CS) is a rare autoimmune disease, complicated by a variety of cardiac manifestations. This case report represents the only documented case in the Republic of Cyprus. It describes the experience of a 23- year-old woman with CS who presented with newly diagnosed, severe aortic regurgitation (AR) and suspected endocarditis. The patient was initially treated successfully with a Ross procedure, but the recurrence of acute AR a few years later, led to the decision to treat her with a mechanical valve replacement, minimising complications and providing as permanent of a surgical solution as possible. This case demonstrates the importance of individualising treatment for such patients.

摘要

科根综合征(CS)是一种罕见的自身免疫性疾病,常伴有多种心脏表现。本病例报告是塞浦路斯共和国唯一有记录的病例。它描述了一名23岁患有CS的女性的经历,该患者初诊时患有严重的主动脉瓣反流(AR)并疑似心内膜炎。患者最初通过罗斯手术成功治疗,但几年后急性AR复发,导致决定为她进行机械瓣膜置换术,以尽量减少并发症并提供尽可能永久的手术解决方案。该病例证明了对此类患者进行个体化治疗的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3338/12365956/713afafda975/omaf143f1.jpg

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