Gad Maram, Faiq Lanya, Arifagic Emma, Kamougeros Alex, Ioannou Stelios, Shiakos George, Tzanavaros Ioannis
European University Cyprus, School of Medicine, 6 Diogenous Street, Nicosia, Engomi 2404, Cyprus.
Apollonion Private Hospital, Cardiac Innovation Center, Nicosia, Cyprus.
Oxf Med Case Reports. 2025 Aug 20;2025(8):omaf143. doi: 10.1093/omcr/omaf143. eCollection 2025 Aug.
Cogan Syndrome (CS) is a rare autoimmune disease, complicated by a variety of cardiac manifestations. This case report represents the only documented case in the Republic of Cyprus. It describes the experience of a 23- year-old woman with CS who presented with newly diagnosed, severe aortic regurgitation (AR) and suspected endocarditis. The patient was initially treated successfully with a Ross procedure, but the recurrence of acute AR a few years later, led to the decision to treat her with a mechanical valve replacement, minimising complications and providing as permanent of a surgical solution as possible. This case demonstrates the importance of individualising treatment for such patients.
科根综合征(CS)是一种罕见的自身免疫性疾病,常伴有多种心脏表现。本病例报告是塞浦路斯共和国唯一有记录的病例。它描述了一名23岁患有CS的女性的经历,该患者初诊时患有严重的主动脉瓣反流(AR)并疑似心内膜炎。患者最初通过罗斯手术成功治疗,但几年后急性AR复发,导致决定为她进行机械瓣膜置换术,以尽量减少并发症并提供尽可能永久的手术解决方案。该病例证明了对此类患者进行个体化治疗的重要性。