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经尿道前列腺隔离/碎片形成及前列腺动脉栓塞术(PAE)后阴茎头缺血性坏死

Transurethral prostatic sequester/fragment and avascular necrosis of the glans penis after prostatic artery embolization (PAE).

作者信息

Sönksen S E, Rothfuchs D, Mertineit N, Popp F, Habermann C R

机构信息

Catholic Marienkrankenhaus Hamburg, Institut for Diagnostic and Interventional Radiology, Germany.

Bundeswehrkrankenhaus Hamburg, Section VIII - Radiology, Germany.

出版信息

Radiol Case Rep. 2025 Aug 5;20(10):5314-5319. doi: 10.1016/j.radcr.2025.07.007. eCollection 2025 Oct.

DOI:10.1016/j.radcr.2025.07.007
PMID:40843312
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12365831/
Abstract

Minimally invasive treatments like prostatic artery embolization (PAE) are effective, low-morbidity alternatives for managing large-volume benign prostatic hyperplasia. This case report describes a patient with lower urinary tract symptoms and acute urinary retention treated with bilateral PAE. Though initially successful, complications included glans necrosis, urinary tract infection, prostatitis, and urosepsis, all of which resolved. Histological analysis revealed necrotic prostate tissue, and follow-up MRI showed a central prostate defect. No long-term issues were observed. The report underscores the need for awareness of rare complications, proper technique, and understanding vascular anatomy to ensure PAE safety and effectiveness.

摘要

像前列腺动脉栓塞术(PAE)这样的微创治疗方法是治疗大体积良性前列腺增生的有效、低发病率的替代方案。本病例报告描述了一名患有下尿路症状和急性尿潴留的患者接受双侧PAE治疗的情况。虽然最初治疗成功,但并发症包括龟头坏死、尿路感染、前列腺炎和尿脓毒症,所有这些并发症均已痊愈。组织学分析显示前列腺组织坏死,随访MRI显示前列腺中央有缺损。未观察到长期问题。该报告强调需要认识到罕见并发症、掌握正确技术并了解血管解剖结构,以确保PAE的安全性和有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1099/12365831/6ebf07bc0b86/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1099/12365831/fdaf6cc9e11f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1099/12365831/6ebf07bc0b86/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1099/12365831/fdaf6cc9e11f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1099/12365831/6ebf07bc0b86/gr2.jpg

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本文引用的文献

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Prostate artery embolization using n-butyl cyanoacrylate glue for symptomatic benign prostatic hyperplasia: A six-month outcome analysis in 103 patients.采用正丁基氰基丙烯酸酯胶栓塞前列腺动脉治疗有症状的良性前列腺增生:103 例患者的 6 个月疗效分析。
Diagn Interv Imaging. 2024 Apr;105(4):129-136. doi: 10.1016/j.diii.2023.12.006. Epub 2023 Dec 30.
2
Reoperation after surgical treatment for benign prostatic hyperplasia: a systematic review.良性前列腺增生症手术治疗后的再次手术:系统评价。
Front Endocrinol (Lausanne). 2023 Nov 9;14:1287212. doi: 10.3389/fendo.2023.1287212. eCollection 2023.
3
Case report of avascular necrosis of the glans penis after PAE embolization.
阴茎头部动脉栓塞后发生的缺血性坏死病例报告。
BMC Urol. 2023 Mar 4;23(1):31. doi: 10.1186/s12894-023-01201-0.
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Efficacy and safety of prostate artery embolization for patients with lower urinary tract symptoms and indwelling urinary catheter: A retrospective multicenter study.前列腺动脉栓塞术治疗伴有留置导尿管的下尿路症状患者的疗效和安全性:一项回顾性多中心研究。
Diagn Interv Imaging. 2022 Dec;103(12):601-606. doi: 10.1016/j.diii.2022.07.002. Epub 2022 Aug 10.
5
Assessing the Complications of Monopolar Transurethral Resection of the Prostate (M-TURP) Using Clavien-Dindo Complications Grading System.采用 Clavien-Dindo 并发症分级系统评估经尿道前列腺单极切除术(M-TURP)的并发症。
Ethiop J Health Sci. 2022 May;32(3):605-612. doi: 10.4314/ejhs.v32i3.17.
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