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基于影像学的结直肠癌肝转移诊断证据。

Evidence for imaging-based diagnosis of liver metastases from colorectal cancer.

作者信息

Tsurusaki Masakatsu, Sofue Keitaro, Murakami Takamichi, Tanigawa Noboru

机构信息

Department of Radiology, Kansai Medical University Medical Center, 10-15 Fumizono-cho, Moriguchi, Osaka, 570-8503, Japan.

Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, 650-0017, Japan.

出版信息

J Gastroenterol. 2025 Aug 22. doi: 10.1007/s00535-025-02292-2.


DOI:10.1007/s00535-025-02292-2
PMID:40844549
Abstract

Metastatic liver tumors are more common than primary liver cancers and are the most common liver malignancies. Performing B-mode ultrasonography and contrast-enhanced computed tomography is generally necessary for the diagnosis of liver metastases. However, various modalities, including dynamic contrast-enhanced computed tomography and magnetic resonance imaging using liver-specific contrast agents such as gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid, fluorodeoxyglucose positron emission tomography, and a combination of positron emission tomography and computed tomography, are also used. Improvements in imaging technology have made the detection of small liver masses possible, and liver metastases are being diagnosed more frequently, both before and after primary tumor treatment. The diagnosis of liver metastasis is related to treatment, and the benefits of liver resection depend on the primary tumor. For colorectal cancer, resection of liver metastases is beneficial. However, resection is not recommended for pancreatic or biliary tract cancers.

摘要

转移性肝肿瘤比原发性肝癌更常见,是最常见的肝脏恶性肿瘤。一般来说,进行B型超声检查和对比增强计算机断层扫描对于肝转移的诊断是必要的。然而,也会使用各种检查方式,包括动态对比增强计算机断层扫描以及使用如钆乙氧基苄基二乙三胺五乙酸等肝脏特异性造影剂的磁共振成像、氟脱氧葡萄糖正电子发射断层扫描,以及正电子发射断层扫描与计算机断层扫描的联合检查。成像技术的进步使得检测小的肝脏肿块成为可能,并且在原发性肿瘤治疗前后,肝转移的诊断都更加频繁。肝转移的诊断与治疗相关,肝切除的益处取决于原发性肿瘤。对于结直肠癌,切除肝转移灶是有益的。然而,对于胰腺癌或胆管癌,不建议进行切除。

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本文引用的文献

[1]
Preoperative imaging of colorectal liver metastases: what the radiologist and the multidisciplinary team need to know.

Br J Radiol. 2024-10-1

[2]
Diffusion-weighted MRI for predicting and assessing treatment response of liver metastases from CRC - A systematic review and meta-analysis.

Eur J Radiol. 2023-6

[3]
Artificial intelligence in the diagnosis and management of colorectal cancer liver metastases.

World J Gastroenterol. 2022-1-7

[4]
Transient Severe Motion Artifact on Arterial Phase in Gadoxetic Acid-Enhanced Liver Magnetic Resonance Imaging: A Systematic Review and Meta-analysis.

Invest Radiol. 2022-1-1

[5]
Radiomics-Derived Data by Contrast Enhanced Magnetic Resonance in RAS Mutations Detection in Colorectal Liver Metastases.

Cancers (Basel). 2021-1-25

[6]
Radiomics of Liver Metastases: A Systematic Review.

Cancers (Basel). 2020-10-7

[7]
Predictive factors of truncation artifacts in the arterial phase of Gd-EOB-DTPA-enhanced MRI: a nationwide multicenter study.

Jpn J Radiol. 2021-2

[8]
Identification of Predominant Histopathological Growth Patterns of Colorectal Liver Metastasis by Multi-Habitat and Multi-Sequence Based Radiomics Analysis.

Front Oncol. 2020-8-14

[9]
Diagnostic performance of magnetic resonance imaging for colorectal liver metastasis: A systematic review and meta-analysis.

Sci Rep. 2020-2-6

[10]
Imaging of Colorectal Liver Metastases: New Developments and Pending Issues.

Cancers (Basel). 2020-1-8

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