Sharpe J A
Can J Neurol Sci. 1985 Nov;12(4):332-5. doi: 10.1017/s0317167100035472.
Early detection of visual loss caused by tumours of the base of the skull is accomplished by systematic tests of the pregeniculate optic pathway. Even when central acuity is relatively preserved, a relative afferent pupillary defect and reduced color perception yield evidence of impaired optic nerve conduction. Although confrontation tests of the visual fields are useful screening techniques, unexplained symptoms should be pursued with static and kinetic perimetry. Patterns of optic nerve and chiasmal field loss and atrophy of the dis or retinal nerve fibers are imprecise guides to the location of basal skull tumours. Regardless of the pattern of visual field defect, unexplained progressive loss of vision demands intensive neuroradiologic study of the basal cisterns and skull.
通过对膝状前视路进行系统检查可实现对颅底肿瘤所致视力丧失的早期检测。即使中心视力相对保留，相对传入性瞳孔缺陷和色觉减退也能提供视神经传导受损的证据。虽然视野的对照试验是有用的筛查技术，但对于无法解释的症状，应采用静态和动态视野检查进一步检查。视神经和视交叉视野缺损以及视盘或视网膜神经纤维萎缩的模式对于颅底肿瘤的定位并不是精确的指导。无论视野缺损的模式如何，无法解释的进行性视力丧失都需要对脑池和颅骨进行强化神经放射学检查。
