Nau Matthias, Greene Austin, Tarder-Stoll Hannah, Lossio-Ventura Juan Antonio, Pereira Francisco, Chen Janice, Baldassano Christopher, Baker Chris I
National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Department of Psychology, Columbia University, New York, NY, USA.
Nat Commun. 2025 Aug 23;16(1):7865. doi: 10.1038/s41467-025-62375-9.
When recalling past events, patterns of gaze position and neural activity resemble those observed during the original experience. We hypothesized that these two phenomena, known as gaze reinstatement and neural reactivation, are linked through a common process that underlies the reinstatement of past experiences during memory retrieval. Here, we tested this proposal based on the viewing and recall of a narrative movie, which we assessed through functional magnetic resonance imaging, deep learning-based gaze prediction, and language modeling of spoken recall. In line with key predictions, gaze behavior adhered to the same principles as neural activity; it was event-specific, robust across individuals, and generalized across viewing and recall. Additionally, gaze-dependent brain activity overlapped substantially across tasks. Collectively, these results suggest that retrieval engages mechanisms similar to those that direct our eyes during natural vision, reflecting common constraints within the functional organization of the nervous system. Moreover, they highlight the importance of considering behavioral and neural reinstatement together in our understanding of remembering.
在回忆过去的事件时，注视位置和神经活动模式类似于最初经历时观察到的情况。我们假设，这两种现象，即注视恢复和神经再激活，是通过一个共同的过程联系在一起的，这个过程是记忆检索过程中过去经历恢复的基础。在这里，我们基于对一部叙事电影的观看和回忆来测试这一假设，我们通过功能磁共振成像、基于深度学习的注视预测以及口头回忆的语言建模来进行评估。与关键预测一致，注视行为遵循与神经活动相同的原则；它是特定于事件的，在个体间具有稳健性，并且在观看和回忆中具有普遍性。此外，依赖注视的大脑活动在不同任务中大量重叠。总体而言，这些结果表明，检索所涉及的机制类似于自然视觉中引导我们眼睛的机制，反映了神经系统功能组织内的共同限制。此外，它们强调了在我们对记忆的理解中一起考虑行为和神经恢复的重要性。
