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儿童癌症幸存者放疗后的脾功能

Splenic function post radiation therapy in childhood cancer survivors.

作者信息

Fulbright Joy, Alsman Kyla, Sherman Ashley K, Laurence Kris, Lowry Becky

机构信息

Division of Hematology/Oncology/Bone Marrow Transplant, Children's Mercy, 2401 Gillham Road, Kansas City, MO 64108, USA.

University of Kansas Health System, 2000 Olathe Blvd, Kansas City, KS 66160, USA.

出版信息

Clin Transl Radiat Oncol. 2025 Apr 13;53:100961. doi: 10.1016/j.ctro.2025.100961. eCollection 2025 Jul.

DOI:10.1016/j.ctro.2025.100961
PMID:40851779
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12368967/
Abstract

Study evaluated splenic function in childhood cancer survivors (CCS) who had received radiation to the spleen utilizing pRBC PIT (vesiculated erythrocytes) count compared to a non-radiated control group. Those exposed to < 20 Gy of radiation had PIT counts not significantly different from the control group. There was trend for higher pRBC PIT count in those exposed to higher doses of radiation.

摘要

该研究利用经泡状红细胞计数评估接受过脾脏放疗的儿童癌症幸存者（CCS）的脾脏功能，并与未接受放疗的对照组进行比较。接受小于20 Gy辐射的患者的泡状红细胞计数与对照组无显著差异。接受更高剂量辐射的患者的经泡状红细胞计数有升高趋势。

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本文引用的文献

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