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产后假性腺瘤性垂体炎酷似垂体大腺瘤:一例报告及文献复习

Postpartum Pseudoadenomatous Hypophysitis Simulating a Pituitary Macroadenoma: A Case Report and Literature Review.

作者信息

Mohammed Elkorno, Yassaad Oudrhiri Mohammed, Hajar Elkorno, Abdessamad Elouahabi, Nadia Cherradi, Hafssa Elouazzani, Yasser Arkha

机构信息

Department of Neurosurgery, Specialty Hospital, CHU Ibn Sina, Mohammed V University, Rabat, Morocco.

Department of Anapathology, Specialty Hospital, CHU Ibn Sina, Mohammed V University, Rabat, Morocco.

出版信息

Asian J Neurosurg. 2025 Apr 24;20(3):621-626. doi: 10.1055/s-0045-1808057. eCollection 2025 Sep.

Abstract

Inflammatory hypothalamo-hypophyseal disorders are uncommon, representing only 1% of hypophyseal lesions. Among these, postpartum lymphocytic hypophysitis emerges as a particularly notable etiology. As a relatively recent entity, its recognition mandates a multidisciplinary approach to ensure preservation of compromised vital prognosis and amelioration of associated neuro-ophthalmologic and/or hypophyseal manifestations. We present a remarkable case of lymphocytic hypophysitis in a 32-year-old woman, unveiled during the postpartum period. Despite employing magnetic resonance imaging (MRI), preoperative diagnosis remained challenging. Surgical intervention became imperative due to progressive visual impairments. Postoperative course demonstrated favorable evolution, characterized by significant enhancement in visual acuity and normalization of cerebral MRI findings during follow-up.

摘要

炎症性下丘脑 - 垂体疾病并不常见,仅占垂体病变的1%。其中,产后淋巴细胞性垂体炎是一种特别值得注意的病因。作为一个相对较新的病种,对其的认识需要多学科方法,以确保维持受损的重要预后并改善相关的神经眼科和/或垂体表现。我们报告一例32岁女性产后淋巴细胞性垂体炎的显著病例。尽管采用了磁共振成像(MRI),术前诊断仍具有挑战性。由于视力进行性损害,手术干预势在必行。术后病程显示良好的进展,随访期间视力显著提高,脑MRI结果恢复正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/937c/12370331/4145e81b94be/10-1055-s-0045-1808057-i2490026-1.jpg

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