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利用心磁图早期检测马伐卡坦对伴有严重二尖瓣反流的肥厚性梗阻性心肌病的治疗反应

Early Detection of Treatment Response to Mavacamten in Hypertrophic Obstructive Cardiomyopathy With Severe Mitral Regurgitation Using Magnetocardiography.

作者信息

Suwalski Phillip, Satilmis Gamze, Reinthaler Markus, Landmesser Ulf, Heidecker Bettina

机构信息

Deutsches Herzzentrum der Charité - Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt - Universität zu Berlin Berlin Germany.

Institute of Biomaterial Science and Berlin-Brandenburg Centre for Regenerative Therapies (BCRT) Hereon Helmholtz-Zentrum Geesthacht Teltow Germany.

出版信息

Clin Case Rep. 2025 Aug 20;13(8):e70667. doi: 10.1002/ccr3.70667. eCollection 2025 Aug.

Abstract

Recent evidence highlights the efficacy of mavacamten in reducing left ventricular outflow tract (LVOT) gradients in patients with hypertrophic cardiomyopathy (HCM), which is illustrated in this case. Additionally, the potential of magnetocardiography (MCG) as a novel, objective diagnostic and monitoring tool for nonischemic cardiomyopathies is demonstrated.

摘要

近期证据突显了马伐卡坦在降低肥厚型心肌病(HCM)患者左心室流出道(LVOT)梯度方面的疗效,本病例即说明了这一点。此外,还展示了心磁图(MCG)作为一种用于非缺血性心肌病的新型客观诊断和监测工具的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5657/12368278/a67ebbbbab6d/CCR3-13-e70667-g004.jpg

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