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一名青少年男性胰腺淋巴管瘤未经手术治疗:一例罕见病例报告。

Pancreatic lymphangioma in an adolescent male managed without surgery: a rare case report.

作者信息

Safeer Deedat, Fernandopulle Nilesh, Keppetiyagama Chathuranga, Subasinghe Duminda

机构信息

Department of Surgery, Faculty of Medicine, University of Colombo, No. 25, P.O. Box 271, Kynsey Road, Colombo 08, Sri Lanka.

University Surgical Unit, The National Hospital of Sri Lanka, Colombo 10, Sri Lanka.

出版信息

J Surg Case Rep. 2025 Aug 21;2025(8):rjaf629. doi: 10.1093/jscr/rjaf629. eCollection 2025 Aug.

DOI:10.1093/jscr/rjaf629
PMID:40852636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12370247/
Abstract

Pancreatic lymphangiomas are extremely rare benign cystic lesions of the pancreas, with fewer than 100 cases reported in the literature. They can mimic other cystic pancreatic neoplasms, posing a diagnostic challenge. This case adds to the limited literature and supports conservative management as a safe option in selected patients. A 15-year-old South Asian male presented with right-sided upper abdominal pain persisting for 5 months. Imaging revealed a large, multiloculated cystic lesion involving the neck and body of the pancreas. Aspiration cytology and cyst fluid analysis (low carcinoembryonic antigen, elevated amylase, lymphocytes) were suggestive of pancreatic lymphangioma. The patient became asymptomatic and was managed conservatively with close monitoring. No surgical intervention was performed. This case demonstrates that conservative management of pancreatic lymphangiomas may be appropriate in asymptomatic or minimally symptomatic adolescents with benign imaging and biochemical features. It reinforces the importance of individualized treatment to avoid unnecessary surgery.

摘要

胰腺淋巴管瘤是极其罕见的胰腺良性囊性病变,文献报道的病例不足100例。它们可模仿其他胰腺囊性肿瘤,带来诊断挑战。本病例补充了有限的文献资料,并支持在特定患者中采用保守治疗作为一种安全选择。一名15岁的南亚男性因右侧上腹部疼痛持续5个月就诊。影像学检查发现一个累及胰腺颈部和体部的巨大多房囊性病变。抽吸细胞学检查和囊液分析(癌胚抗原水平低、淀粉酶升高、淋巴细胞)提示为胰腺淋巴管瘤。患者症状消失,通过密切监测进行保守治疗。未进行手术干预。该病例表明,对于无症状或症状轻微、具有良性影像学和生化特征的青少年胰腺淋巴管瘤患者,保守治疗可能是合适的。这强化了个体化治疗以避免不必要手术的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ebf/12370247/c141c64e210f/rjaf629f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ebf/12370247/7fcb968f9752/rjaf629f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ebf/12370247/c141c64e210f/rjaf629f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ebf/12370247/7fcb968f9752/rjaf629f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ebf/12370247/c141c64e210f/rjaf629f2.jpg

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本文引用的文献

1
Pancreatic Cystic Neoplasms: Diagnosis and Management.胰腺囊性肿瘤:诊断与管理
Diagnostics (Basel). 2023 Jan 5;13(2):207. doi: 10.3390/diagnostics13020207.
2
Cystic pancreatic lymphangioma diagnosed with endoscopic ultrasound-guided fine needle aspiration.经内镜超声引导下细针穿刺活检诊断为胰腺囊性淋巴管瘤。
Endosc Ultrasound. 2017 Mar-Apr;6(2):136-139. doi: 10.4103/2303-9027.204807.
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Lymphoepithelial Cyst of the Pancreas.胰腺淋巴上皮囊肿
Case Rep Gastroenterol. 2016 May 19;10(1):181-92. doi: 10.1159/000445373. eCollection 2016 Jan-Apr.
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Clinical and radiological feature of lymphoepithelial cyst of the pancreas.胰腺淋巴上皮囊肿的临床及影像学特征
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Lymphoepithelial cysts of the pancreas: the use of endoscopic ultrasound-guided fine-needle aspiration in diagnosis.胰腺淋巴上皮囊肿:内镜超声引导下细针穿刺抽吸术在诊断中的应用
Can J Gastroenterol. 2010 Jun;24(6):348-50. doi: 10.1155/2010/456867.