Shibata Reo, Suzuki Satoshi, Takeda Kazuki, Iga Takahito, Okubo Toshiki, Ozaki Masahiro, Tsuji Osahiko, Nagoshi Narihito, Matsumoto Morio, Nakamura Masaya, Watanabe Kota
Department of Orthopedic Surgery, Keio University School of Medicine, Shinjuku-ku, Japan.
Global Spine J. 2025 Aug 25:21925682251371620. doi: 10.1177/21925682251371620.
Study DesignRetrospective cohort study.ObjectiveThis study aimed to determine whether the outcomes of posterior correction and fusion surgery (PSF) in patients with residual adolescent idiopathic scoliosis (AIS) during adulthood (Lenke type 5 AdIS) are inferior to those in patients with AIS treated during adolescence.MethodsWe retrospectively evaluated 48 patients with type 5 AdIS who underwent PSF after 20 years old. As controls, we selected 67 patients with type 5 AIS who underwent PSF before 18 years old. Both groups were matched based on the preoperative thoracic and thoracolumbar/lumbar Cobb angles, resulting in 33 patients in each group. We compared preoperative and postoperative radiographic parameters and SRS-22 scores between the 2 groups.ResultsPreoperatively, the AdIS group had significantly lower flexibility index (59.0% ± 13.0% vs 66.6% ± 16.7%; = 0.01). The preoperative SRS-22 scores for pain and mental health domain were significantly worse in the AdIS group (pain, 3.9 ± 0.8 vs 4.3 ± 0.7, < 0.01; mental health, 3.6 ± 0.8 vs 4.2 ± 0.6, < 0.01). The AdIS group had significantly more fused vertebrae and longer intraoperative time than the AIS group. Postoperatively, lumber Cobb angle (16.1° ± 5.6° vs 8.6° ± 4.0°, < 0.01) and correction rate were both less favorable in the AdIS group. Both pain and mental health scores remained significantly worse in the AdIS group (pain: AdIS, 4.3 ± 0.6 vs AIS, 4.7 ± 0.3; < 0.01; mental health: AdIS, 4.1 ± 0.7 vs AIS, 4.5 ± 0.5; = 0.02).ConclusionPatients with type 5 AdIS had a similar correction of the major curve as those with AIS; however, the surgery was more invasive, with inferior postoperative clinical outcomes, than those with AIS. These findings suggest that the surgical timing should be carefully considered in patients with type 5 AIS to optimize outcomes.
研究设计
回顾性队列研究。
目的
本研究旨在确定成年期残留青少年特发性脊柱侧凸(AIS)患者(Lenke 5型成年特发性脊柱侧凸)后路矫正融合手术(PSF)的疗效是否劣于青春期接受治疗的AIS患者。
方法
我们回顾性评估了48例20岁后接受PSF的5型成年特发性脊柱侧凸患者。作为对照,我们选择了67例18岁前接受PSF的5型AIS患者。两组根据术前胸椎和胸腰段/腰椎Cobb角进行匹配,每组各33例。我们比较了两组术前和术后的影像学参数及SRS-22评分。
结果
术前,成年特发性脊柱侧凸组的柔韧性指数显著更低(59.0%±13.0%对66.6%±16.7%;P = 0.01)。成年特发性脊柱侧凸组术前SRS-22疼痛和心理健康领域评分显著更差(疼痛:3.9±0.8对4.3±0.7,P < 0.01;心理健康:3.6±0.8对4.2±0.6,P < 0.01)。成年特发性脊柱侧凸组融合椎体更多,手术时间比AIS组更长。术后,成年特发性脊柱侧凸组腰椎Cobb角(16.1°±5.6°对8.6°±4.0°,P < 0.01)和矫正率均较差。成年特发性脊柱侧凸组疼痛和心理健康评分仍显著更差(疼痛:成年特发性脊柱侧凸组4.3±0.6对AIS组4.7±0.3;P < 0.01;心理健康:成年特发性脊柱侧凸组4.1±0.7对AIS组4.5±0.5;P = 0.02)。
结论
5型成年特发性脊柱侧凸患者主弯矫正情况与AIS患者相似;然而,与AIS患者相比,该手术创伤更大,术后临床疗效更差。这些发现表明,对于5型AIS患者应仔细考虑手术时机以优化疗效。