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机器人辅助与单孔肺叶切除术治疗肺癌后的疼痛与恢复:一项对比分析

Pain and recovery after robotic vs. uniportal lobectomy for lung cancer: a comparative analysis.

作者信息

Tulinský Lubomír, Jarošová Nikol, Adamica Dávid, Bujok Petr, Mitták Marcel, Kondé Adéla, Martínek Lubomír

机构信息

Department of Surgery, University Hospital Ostrava, 17.Listopadu 1790, Ostrava, Czech Republic.

Department of Surgical Studies, Faculty of Medicine, University of Ostrava, Syllabova 19, Ostrava, Czech Republic.

出版信息

Surg Endosc. 2025 Aug 25. doi: 10.1007/s00464-025-12083-8.

Abstract

BACKGROUND

Minimally invasive thoracic surgery techniques, such as robotic-assisted thoracic surgery (RATS) and uniportal video-assisted thoracoscopic surgery (UVATS), have revolutionized lung cancer treatment. However, comparative data on postoperative pain and functional recovery remain limited. This cohort study evaluates differences in pain intensity and pain-related activity limitations following radical lobectomy for lung cancer.

METHODS

A total of 140 patients undergoing lobectomy (70 RATS, 70 UVATS) were prospectively assessed. Pain intensity was measured using the Visual Analog Scale (VAS), and functional impact was evaluated with the Daily Activity Pain Interference Questionnaire (DAPIQ) on postoperative days 3 and 14. Demographic factors, including sex and body mass index (BMI), were analyzed as potential modifiers.

RESULTS

Patients in the RATS group reported significantly higher VAS scores compared to the UVATS group on postoperative day 3 (5.8 ± 2.0 vs. 3.8 ± 1.6; p < 0.001) and day 14 (2.7 ± 1.1 vs. 2.2 ± 1.1; p = 0.001). Only 17.1% of RATS patients were pain-free by day 14, compared to 34.3% in the UVATS group (p = 0.016). The likelihood of pain-related activity interference was 3.8 times higher in the RATS group. Female sex and lower BMI were associated with worse pain outcomes. VAS scores strongly correlated with DAPIQ results (β = 0.43).

CONCLUSIONS

This study demonstrates that RATS is associated with significantly greater postoperative pain and functional limitations than UVATS following lobectomy for lung cancer. These findings underscore the importance of tailored pain management strategies in robotic thoracic surgery, particularly for higher-risk subgroups. Integration of the DAPIQ questionnaire into routine postoperative care may enhance functional recovery monitoring.

摘要

背景

微创胸外科技术,如机器人辅助胸外科手术(RATS)和单孔电视辅助胸腔镜手术(UVATS),彻底改变了肺癌的治疗方式。然而,关于术后疼痛和功能恢复的比较数据仍然有限。这项队列研究评估了肺癌根治性肺叶切除术后疼痛强度和与疼痛相关的活动受限情况的差异。

方法

前瞻性评估了总共140例行肺叶切除术的患者(70例RATS手术,70例UVATS手术)。使用视觉模拟量表(VAS)测量疼痛强度,并在术后第3天和第14天使用日常活动疼痛干扰问卷(DAPIQ)评估功能影响。分析了包括性别和体重指数(BMI)在内的人口统计学因素作为潜在的调节因素。

结果

RATS组患者在术后第3天(5.8±2.0 vs. 3.8±1.6;p<0.001)和第14天(2.7±1.1 vs. 2.2±1.1;p = 0.001)的VAS评分显著高于UVATS组。到第14天时,只有17.1%的RATS患者无疼痛,而UVATS组为34.3%(p = 0.016)。RATS组与疼痛相关的活动干扰可能性高3.8倍。女性和较低的BMI与更差的疼痛结果相关。VAS评分与DAPIQ结果密切相关(β = 0.43)。

结论

本研究表明,肺癌肺叶切除术后,RATS与比UVATS明显更大的术后疼痛和功能受限相关。这些发现强调了在机器人胸外科手术中制定个性化疼痛管理策略的重要性,特别是对于高风险亚组。将DAPIQ问卷纳入常规术后护理可能会加强对功能恢复的监测。

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