Tomić R, Bergman B, Hietala S O, Angström T
Eur Urol. 1985;11(6):378-81. doi: 10.1159/000472544.
In 48 patients with prostatic carcinoma two types of cell patterns were found at fine-needle aspiration biopsy at follow-up 6 and 12 months after orchiectomy: (1) unmodified carcinoma cells or (2) carcinoma cells with regressive changes. Objective clinical regression at 36 months was significantly more frequent in patients with regressively transformed cancer cells at 6 and/or 12 months than in patients with unmodified carcinoma cells: 73 and 32%, respectively. Ten percent of the patients with regressively transformed carcinoma cells and 41% of the patients with unmodified cancer cells died of prostatic carcinoma. The cytologic findings at 6 and/or 12 months after orchiectomy is thus of importance for predicting the prognosis.
在48例前列腺癌患者中，睾丸切除术后6个月和12个月的细针穿刺活检发现了两种细胞模式：（1）未改变的癌细胞或（2）具有退行性改变的癌细胞。6个月和/或12个月时癌细胞发生退行性转变的患者在36个月时出现客观临床缓解的频率显著高于未改变癌细胞的患者，分别为73%和32%。癌细胞发生退行性转变的患者中有10%、未改变癌细胞的患者中有41%死于前列腺癌。因此，睾丸切除术后6个月和/或12个月的细胞学检查结果对预测预后具有重要意义。
