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白化大鼠的视动性眼震取决于刺激模式。

Optokinetic nystagmus in albino rats depends on stimulus pattern.

作者信息

Sirkin D W, Hess B J, Precht W

出版信息

Exp Brain Res. 1985;61(1):218-21. doi: 10.1007/BF00235639.

DOI:10.1007/BF00235639
PMID:4085600
Abstract

Ocular responses to optokinetic stimulation were reexamined in adult albino rats of two different strains. Eye movements were measured in head-restrained animals using the search coil method. In contrast to some previous results, the albino rats showed optokinetic nystagmus, and some of them made responses comparable to those previously recorded from pigmented rats. However, the type of stimulus pattern used to elicit optokinetic nystagmus proved to be crucial for albino rats. The deficit is attributed to abnormalities in the albino rat's visual sensory apparatus. Inverted optokinetic nystagmus was elicited in albino rats by restricting the optokinetic stimulation to the anterior visual field of both eyes. The same phenomenon has been observed previously in albino rabbits and mice, and has been suggested to be due to the abnormally small number of uncrossed optic nerve fibers in albinos.

摘要

在两种不同品系的成年白化大鼠中重新检查了对视动刺激的眼部反应。使用搜索线圈法在头部固定的动物中测量眼球运动。与之前的一些结果相反,白化大鼠表现出视动性眼球震颤,其中一些大鼠的反应与之前在有色大鼠中记录的反应相当。然而,事实证明,用于引发视动性眼球震颤的刺激模式类型对白化大鼠至关重要。这种缺陷归因于白化大鼠视觉感觉器官的异常。通过将视动刺激限制在双眼的前视野,在白化大鼠中引发了反向视动性眼球震颤。之前在白化兔和小鼠中也观察到了同样的现象,有人认为这是由于白化动物中未交叉的视神经纤维数量异常少所致。

相似文献

1
Optokinetic nystagmus in albino rats depends on stimulus pattern.白化大鼠的视动性眼震取决于刺激模式。
Exp Brain Res. 1985;61(1):218-21. doi: 10.1007/BF00235639.
2
Vestibulo-ocular and optokinetic deficits in albinos with congenital nystagmus.患有先天性眼球震颤的白化病患者的前庭眼反射和视动性缺陷。
Invest Ophthalmol Vis Sci. 1984 Jun;25(6):739-45.
3
Optokinetic eye movements in albino rabbits: inversion in anterior visual field.白化兔的视动性眼动:前视野反转
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4
Eye movements of human albinos.
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Horizontal optokinetic ocular nystagmus in the pigmented rat.有色大鼠的水平视动性眼球震颤
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Albino mice as an animal model for infantile nystagmus syndrome.白化病小鼠作为婴儿型眼球震颤综合征的动物模型。
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The oculomotor behaviour of human albinos.人类白化病患者的眼球运动行为。
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Optokinetic, vestibular, and optokinetic-vestibular responses in albino and pigmented rats.白化病大鼠和有色大鼠的视动、前庭及视动-前庭反应。
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Optokinetic deficits in albino ferrets (Mustela putorius furo): a behavioral and electrophysiological study.白化雪貂(白鼬)的视动缺陷:一项行为学和电生理学研究。

本文引用的文献

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[Relation of the direction of optical stimulation to the type of reflex of the oculomotor muscles].[光刺激方向与动眼肌反射类型的关系]
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Inappropriate use of albino animals as models in research.在研究中不恰当地使用白化动物作为模型。
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Optokinetic, vestibular, and optokinetic-vestibular responses in albino and pigmented rats.白化病大鼠和有色大鼠的视动、前庭及视动-前庭反应。
Pflugers Arch. 1982 Mar;393(1):42-4. doi: 10.1007/BF00582389.
5
Quantitative analysis of a cross-sectional area of the optic nerve: a comparison between albino and pigmented rats.视神经横截面积的定量分析:白化大鼠与有色大鼠的比较。
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The horizontal optokinetic nystagmus in the cat.猫的水平视动性眼球震颤。
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Photically evoked responses in the visual system of rats exposed to continuous light.持续光照下大鼠视觉系统中的光诱发反应。
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The organization of the retinal projection to the dorsal lateral geniculate nucleus in pigmented and albino rats.有色和白化大鼠视网膜向背外侧膝状核投射的组织学研究
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