[Effect of EDTA on the activity of aminolevulinic dehydratase in vitro and in vivo].

To blood samples taken from persons who are not exposed to the effect of lead, ions Pb++ were added. Then lowering of the activity of aminolevulinic dehydratase (ALAD) in proportion to an amount of lead added was observed. Parallel introduction of ions Pb++ and EDTA prevented a significant lowering of ALAD activity. The persons who were exposed to chronic effect of lead, with a lowered activity of ALAD, were given EDTA, as a treatment. Significant increase in the form of doubled activity of the enzyme occurred in the period between 8-16 day of treatment.