阿根廷云加斯雨林蝙蝠体内的登革热病毒中和抗体
Dengue Virus Neutralizing Antibodies in Bats from the Yungas Rainforest, Argentina.
作者信息
Rucci Kevin A, Ferro Ignacio, Castilla M Cecilia, Schaaf Alejandro A, Aguilar Javier, Farias Adrián A, Urquizo José H, Murgia Agustina, Spinsanti Lorena, Diaz Adrián
机构信息
Laboratorio de Arbovirus, Facultad de Ciencias Médicas, Instituto de Virología "Dr. J.M. Vanella" (InViV), Universidad Nacional de Córdoba, X5000HUA, Córdoba, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), C1425FQB, Buenos Aires, Argentina.
出版信息
Ecohealth. 2025 Aug 26. doi: 10.1007/s10393-025-01751-9.
This study explores the exposure of sylvatic bats to dengue virus (DENV) by detecting neutralizing antibodies against the virus in the Argentinean Yungas. Blood samples from 143 bats were tested using PRNT, revealing DENV-1 antibodies in three individuals (Sturnira lilium, S. erythromos, Artibeus planirostris) from sylvatic habitats of Jujuy. Presence of DENV-1 antibodies in sylvatic bats suggests potential exposure to the virus in wild areas, indicating the potential endemicity of DENV in subtropical areas of Argentina. Further research is needed to understand the mechanism through which DENV has potentially established in wild areas of Argentina and the role of bats as host for DENV.
本研究通过检测阿根廷永加斯地区野生蝙蝠体内针对登革病毒（DENV）的中和抗体，探索野生蝙蝠对登革病毒的暴露情况。使用空斑减少中和试验（PRNT）对143只蝙蝠的血液样本进行检测，结果显示，来自胡胡伊省野生栖息地的3只蝙蝠（厄瓜多尔黄肩蝠、红肩果蝠、长吻果蝠）体内存在DENV-1抗体。野生蝙蝠体内存在DENV-1抗体表明其在野生区域可能接触过该病毒，这意味着登革病毒在阿根廷亚热带地区可能呈地方性流行。需要进一步开展研究，以了解登革病毒在阿根廷野生区域可能的传播机制，以及蝙蝠作为登革病毒宿主所起的作用。
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