Tanabe A, Kondo Y, Toriumi T
Nihon Yakurigaku Zasshi. 1985 Sep;86(3):175-9. doi: 10.1254/fpj.86.175.
The effect of HPS (halofuginonepolystyrene sulfonate), a derivative of halofuginone with lower toxicity, on natural leucocytozoon and coccidial infection in broiler chickens was evaluated in a floor pen trial. The experiment was conducted from one day to 10 weeks of age. On leucocytozoon infection, HPS added to the diet was completely effective at 60 ppm, fairly effective at 40 ppm and ineffective at 20 ppm. On the other hand, HPS concentrations of 20 ppm, 40 ppm and 60 ppm were completely effective on coccidial infection. HPS at 40 ppm which corresponds to the recommended level of halofuginone (3 ppm) and at 60 ppm had no adverse effect on the weight gain in experimental birds.
在地面平养试验中评估了毒性较低的常山酮衍生物HPS（卤夫酮聚苯乙烯磺酸盐）对肉鸡自然感染白细胞原虫和球虫的影响。试验从1日龄进行至10周龄。对于白细胞原虫感染，日粮中添加60 ppm的HPS完全有效，40 ppm时效果尚可，20 ppm时无效。另一方面，20 ppm、40 ppm和60 ppm的HPS浓度对球虫感染完全有效。相当于推荐剂量常山酮（3 ppm）的40 ppm HPS以及60 ppm HPS对试验鸡的体重增加没有不良影响。
