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12岁及以上男性膳食肌酸摄入量与精子发生血清生物标志物之间的关联。

Association between dietary creatine intake and serum biomarkers of spermatogenesis in males aged 12 years and older.

作者信息

Nedeljkovic David, Todorovic Nikola, Stea Tonje Holte, Engeset Dagrun, Ostojic Sergej M

机构信息

Applied Bioenergetics Lab, Faculty of Sport and Physical Education, University of Novi Sad, Novi Sad, Serbia.

Department of Health and Nursing Sciences, University of Agder, Kristiansand, Norway.

出版信息

Reprod Fertil. 2025 Sep 3;6(3). doi: 10.1530/RAF-25-0009. Print 2025 Jul 1.

Abstract

LAY SUMMARY

Creatine is a nutrient that helps provide energy to different parts of the body, including the testes. Since making sperm takes a lot of energy, creatine might play a role in supporting sperm health. Some studies suggest it could help, while others raise concerns. However, it is still unclear what effect, if any, creatine from food has on sperm. To learn more, we looked at data from over 1,300 males in the US, aged 12 and older. We compared how much creatine they got from their diet with levels of two hormones in the blood that are related to sperm production. We found no strong link between dietary creatine and these hormone levels. This suggests that creatine from food probably does not have a major effect - good or bad - on male reproductive health. Since this study used existing data and did not test creatine directly in an experiment, we cannot say for sure if creatine causes any changes. More research, especially studies that look directly at sperm, is needed to better understand how creatine might affect fertility.

摘要

简要概述

肌酸是一种营养物质,有助于为身体的不同部位提供能量,包括睾丸。由于制造精子需要大量能量,肌酸可能在支持精子健康方面发挥作用。一些研究表明它可能有帮助,而另一些研究则引发担忧。然而,食物中的肌酸对精子究竟有什么影响(如果有影响的话)仍不清楚。为了进一步了解,我们查看了来自美国1300多名12岁及以上男性的数据。我们将他们从饮食中获取的肌酸量与血液中与精子产生相关的两种激素水平进行了比较。我们发现饮食中的肌酸与这些激素水平之间没有紧密联系。这表明食物中的肌酸可能对男性生殖健康没有重大影响——无论是好是坏。由于这项研究使用的是现有数据,没有在实验中直接测试肌酸,我们不能确定肌酸是否会导致任何变化。需要更多的研究,特别是直接观察精子的研究,以更好地了解肌酸可能如何影响生育能力。

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