Mikkelsen A, Stokke B T, Elgsaeter A
Int J Biomed Comput. 1985 Nov;17(3-4):215-26. doi: 10.1016/0020-7101(85)90024-8.
A computerized low-shear pendulum viscoelastometer that is well suited for measurements of the viscoelastic properties of soft biogels is described. The instrument has three modes of operation: (i) measurement of dynamic elastic moduli, (ii) stress relaxation, and (iii) shear creep-creep recovery. The main mechanical parts of the instrument include a specimen cuvette and a pendulum with a thin metal plate extending into the specimen cuvette. The cuvette and pendulum can undergo independent angular movements relative to a horizontal axis located about 12 cm above the specimen cuvette. The absolute angular position of the cuvette is under on-line computer control through a stepping motor driven micrometer. The angular position of the pendulum relative to the cuvette is measured using an inductive position detector. The necessary software for automatic operation, data acquisition and processing has been developed for all the three modes of operation. The instrument is well suited for measurements of dynamic elastic moduli in the range 0.02-150 dyn/cm2. Calibration data obtained using 100% ethanol are presented. The instrument suitability for measurements of stress relaxation and shear creep-creep recovery is illustrated by presenting the results of such measurements on a 5.5-mg/ml erythrocyte spectrin gel in isotonic solution.
本文描述了一种计算机化的低剪切摆式粘弹性仪，它非常适合测量软生物凝胶的粘弹性特性。该仪器有三种操作模式：（i）动态弹性模量测量，（ii）应力松弛，以及（iii）剪切蠕变 - 蠕变恢复。仪器的主要机械部件包括一个样品比色皿和一个带有延伸到样品比色皿中的薄金属板的摆锤。比色皿和摆锤可相对于位于样品比色皿上方约12厘米处的水平轴进行独立的角运动。比色皿的绝对角位置通过步进电机驱动的测微计在线计算机控制。摆锤相对于比色皿的角位置使用感应式位置检测器进行测量。针对所有三种操作模式开发了自动操作、数据采集和处理所需的软件。该仪器非常适合测量0.02 - 150 dyn/cm2范围内的动态弹性模量。给出了使用100%乙醇获得的校准数据。通过展示在等渗溶液中5.5 mg/ml红细胞血影蛋白凝胶上的此类测量结果，说明了该仪器对应力松弛和剪切蠕变 - 蠕变恢复测量的适用性。
