Goyal Vikas Deep, Varshney Amit, Pahade Akhilesh
Surgery, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, IND.
Internal Medicine, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, IND.
Cureus. 2025 Jul 25;17(7):e88742. doi: 10.7759/cureus.88742. eCollection 2025 Jul.
Objectives The aim of the study was to evaluate the effect of autologous blood transfusion on the requirement of allogeneic blood products and the change in hemoglobin levels in open heart procedures. Patients and methods The study included 59 patients who underwent open heart procedures from July 2020 to August 2022. Group 1 (35 patients) received an autologous blood transfusion, and group 2 (24 patients) did not receive an autologous transfusion. The requirement of allogeneic blood components and other demographic and clinical parameters were compared between the two groups. Results In the autologous group, 22 (62.9%) patients underwent valve replacement, 9 (25.7%) patients underwent on-pump coronary artery bypass grafting, and 4 (11.4%) patients other procedures (atrial septal defect closure, pulmonary stenosis), whereas in the non-autologous group, 19 (79.7%) patients underwent valve replacement, 3 (12.5%) patients underwent on-pump coronary artery bypass, and 2 (8.33%) patients underwent other on pump procedures. The comparison of the change in hemoglobin levels after surgery between the two groups was statistically significant, with greater change seen in the autologous group. The requirement for blood products was more in group 2, but the difference was not statistically significant. Conclusion Use of autologous blood during cardiac surgery on pump did not reveal any significant advantage. On the contrary, change in hemoglobin from preoperative to postoperative levels was greater in the autologous group as compared to the non-autologous group.
目的 本研究的目的是评估自体输血对心脏直视手术中异体血制品需求及血红蛋白水平变化的影响。
患者与方法 本研究纳入了2020年7月至2022年8月期间接受心脏直视手术的59例患者。第1组(35例患者)接受自体输血,第2组(24例患者)未接受自体输血。比较两组之间异体血成分的需求以及其他人口统计学和临床参数。
结果 在自体输血组中,22例(62.9%)患者接受瓣膜置换术,9例(25.7%)患者接受体外循环冠状动脉搭桥术,4例(11.4%)患者接受其他手术(房间隔缺损修补术、肺动脉狭窄手术);而在非自体输血组中,19例(79.7%)患者接受瓣膜置换术,3例(12.5%)患者接受体外循环冠状动脉搭桥术,2例(8.33%)患者接受其他体外循环手术。两组术后血红蛋白水平变化的比较具有统计学意义,自体输血组变化更大。第2组对血制品的需求更多,但差异无统计学意义。
结论 在心脏体外循环手术中使用自体血未显示出任何显著优势。相反,与非自体输血组相比,自体输血组术前至术后血红蛋白的变化更大。