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收缩期小动脉中的血流。

Blood flow in contracting arterioles.

作者信息

Schmid-Schönbein G W, Murakami H

出版信息

Int J Microcirc Clin Exp. 1985;4(4):311-28.

PMID:4086188
Abstract

Blood flow in contracting arterioles with non-circular cross-sections due to endothelial protrusions is investigated. The flow field was determined for a viscous Newtonian fluid with a numerical computation from electron micrographs of arteriolar crossections in skeletal muscle at different stages of contraction. The results indicate that the flow field in such vessels deviates from Poiseuille flow for circular tubes of equal cross-sectional area in several respects: the resistance is elevated, the ratio of maximum and mean velocity is increased above the value of 2 for Poiseuille flow, and the wall shear stress is nonuniform with a maximum at the tip of local endothelial projections and near zero at endothelial cell junctions. The average wall shear stress is less than in circular vessels with equal lumen crossection and pressure gradient.

摘要

研究了由于内皮细胞突起导致横截面为非圆形的收缩小动脉中的血流情况。通过对骨骼肌中小动脉横截面在不同收缩阶段的电子显微镜照片进行数值计算,确定了粘性牛顿流体的流场。结果表明,此类血管中的流场在几个方面偏离了具有相同横截面积的圆形管的泊肃叶流:阻力升高,最大速度与平均速度之比增加到高于泊肃叶流的2值,壁面剪应力不均匀,在内皮局部突起的尖端处最大,在内皮细胞连接处附近接近于零。平均壁面剪应力小于具有相同管腔横截面积和压力梯度的圆形血管中的平均壁面剪应力。

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引用本文的文献

1
Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats.自发性高血压大鼠中与动脉血压相关的黄嘌呤氧化酶活性
Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4754-9. doi: 10.1073/pnas.95.8.4754.
2
Biomechanics of skeletal muscle capillaries: hemodynamic resistance, endothelial distensibility, and pseudopod formation.骨骼肌毛细血管的生物力学:血流动力学阻力、内皮扩张性和伪足形成。
Ann Biomed Eng. 1995 May-Jun;23(3):226-46. doi: 10.1007/BF02584425.