Boulanger Nathalie, Iijima Hayato, Doi Kandai, Watari Yuya, Kwak Mackenzie, Nakao Ryo, Wikel Stephen
UR 3073: PHAVI: Groupe Borrelia, Institut de Bactériologie, University of Strasbourg, Strasbourg, France.
French National Reference Center for Borrelia, Hôpitaux Universitaires, Strasbourg, France.
Front Microbiol. 2025 Aug 8;16:1632832. doi: 10.3389/fmicb.2025.1632832. eCollection 2025.
Temperate zones of the northern hemisphere are increasingly impacted by human biting ticks and the human pathogens they transmit. The relationships among ticks, hosts, and pathogens are undergoing significant changes with consequences for human health. This northern hemisphere focused review examines human biting ticks and the disease causing agents they transmit as increasing public health threats due to geographic range expansion, increasing size of tick populations, emergence of newly recognized pathogens, introduction of invasive tick species that are resulting in part from changing weather patterns, land use modifications, biodiversity loss, and human activities/behaviors; all of which result in significant challenges for tick control and disease prevention. As a result of these evolving interactions and the resulting threats they pose, there exist critical needs to implement existing and develop novel tools and strategies to prevent tick bites, control tick populations, and reduce transmission of tick-borne pathogens. Timely, up to date knowledge of which ticks and tick-borne infectious agents are present within an area is foundational for physicians, public health authorities tasked with disease prevention, and the public. Achieving these objectives poses significant challenges. Here, we examine current medically important tick - host - pathogen relationships in Asia, Europe, and North America.
北半球的温带地区越来越受到叮咬人类的蜱虫及其传播的人类病原体的影响。蜱虫、宿主和病原体之间的关系正在发生重大变化，对人类健康产生影响。这篇以北半球为重点的综述探讨了叮咬人类的蜱虫及其传播的致病因子，它们因地理范围扩大、蜱虫种群规模增加、新发现病原体的出现、入侵蜱虫物种的引入（部分原因是天气模式变化、土地利用改变、生物多样性丧失以及人类活动/行为）而对公共卫生构成越来越大的威胁；所有这些都给蜱虫控制和疾病预防带来了重大挑战。由于这些不断演变的相互作用及其带来的威胁，迫切需要实施现有方法并开发新的工具和策略，以防止蜱虫叮咬、控制蜱虫种群并减少蜱传病原体的传播。及时、最新地了解某个地区存在哪些蜱虫和蜱传感染因子，对医生、负责疾病预防的公共卫生当局以及公众来说至关重要。实现这些目标面临重大挑战。在此，我们研究了亚洲、欧洲和北美洲当前具有重要医学意义的蜱虫 - 宿主 - 病原体关系。
