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全内镜脊柱手术治疗硬膜内病变:创新、挑战及未来前景的系统评价

Full-endoscopic spine surgery for intradural pathologies: A systematic review of innovations, challenges, and future prospects.

作者信息

Dolas Ilyas, Unal Tugrul Cem, Gulsever Cafer Ikbal, Dolen Duygu, Yorukoglu Ali Guven, Sencer Altay

机构信息

Department of Neurosurgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Department of Neurosurgery, Hakkari State Hospital, Hakkari, Turkey.

出版信息

Brain Spine. 2025 Aug 13;5:104392. doi: 10.1016/j.bas.2025.104392. eCollection 2025.

Abstract

INTRODUCTION

Full-endoscopic spinal surgery (monoportal endoscopy) has emerged as a minimally invasive alternative for managing intradural spinal pathologies, offering reduced morbidity and accelerated recovery compared to conventional techniques.

RESEARCH QUESTION

What is the current evidence on the effectiveness, limitations, and future prospects of full-endoscopic spinal surgery for intradural pathologies?

MATERIAL AND METHODS

A systematic review following PRISMA guidelines was conducted. Electronic databases (Cochrane, OVID-MEDLINE, PubMed, Embase, Web of Science, Scopus) were searched for studies published from 2000 to 2024. Studies on full-endoscopic intradural spine surgery, including clinical trials, comparative studies, case reports, and meta-analyses in English, were included. Exclusion criteria involved non-intradural pathologies, biportal techniques, animal studies, and non-English publications. Narrative synthesis was performed due to study heterogeneity.

RESULTS

Thirty studies were reviewed. Full-endoscopic techniques effectively managed conditions such as tethered cord syndrome, spinal arachnoid cysts, intradural extramedullary tumors, Chiari malformation, and select vascular and inflammatory conditions. Benefits included minimal tissue disruption, improved visualization, shorter hospital stays, and reduced complications. Key challenges identified were intraoperative bleeding control, reliable dural closure, and irrigation-related complications like increased intracranial pressure.

DISCUSSION AND CONCLUSION

Full-endoscopic spine surgery demonstrates substantial clinical promise for intradural spinal conditions, significantly reducing morbidity and enhancing recovery. However, addressing current technical challenges is essential. Ongoing technological advancements in imaging, neuronavigation, and robotic-assisted systems, combined with future clinical trials, will be critical for expanding indications and confirming long-term efficacy.

摘要

引言

全内镜脊柱手术(单通道内镜)已成为治疗硬脊膜内脊柱病变的一种微创替代方法,与传统技术相比,具有更低的发病率和更快的恢复速度。

研究问题

全内镜脊柱手术治疗硬脊膜内病变的有效性、局限性和未来前景的当前证据是什么?

材料与方法

按照PRISMA指南进行系统综述。检索电子数据库(Cochrane、OVID-MEDLINE、PubMed、Embase、Web of Science、Scopus),查找2000年至2024年发表的研究。纳入关于全内镜硬脊膜内脊柱手术的研究,包括英文的临床试验、比较研究、病例报告和荟萃分析。排除标准包括非硬脊膜内病变、双通道技术、动物研究和非英文出版物。由于研究的异质性,进行了叙述性综合分析。

结果

共审查了30项研究。全内镜技术有效地治疗了诸如脊髓栓系综合征、脊髓蛛网膜囊肿、硬脊膜内髓外肿瘤、Chiari畸形以及某些血管和炎症性疾病等病症。其益处包括组织破坏最小、视野改善、住院时间缩短和并发症减少。确定的主要挑战是术中出血控制、可靠的硬脊膜闭合以及与冲洗相关的并发症,如颅内压升高。

讨论与结论

全内镜脊柱手术在治疗硬脊膜内脊柱疾病方面显示出巨大的临床前景,显著降低了发病率并促进了恢复。然而,解决当前的技术挑战至关重要。成像、神经导航和机器人辅助系统方面正在进行的技术进步,再加上未来的临床试验,对于扩大适应症和确认长期疗效将至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9700/12375244/a38117bbe562/gr1.jpg

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