Mertz D P, Koch B
MMW Munch Med Wochenschr. 1977 Jul 15;119(28):945-8.
The therapeutic success of fractionated radioiodine treatment of hyperthyroid patients with and without endocrine ophthalmopathy is examined. To achieve a stable euthyroid metabolism, patients with endocrine ophthalmopathy generally need a greater number of treatments with a necessarily higher total dose of radioiodine and longer duration of treatment than hyperthyroid patients without endocrine ophthalmopathy. The average age, the average uptake of 131l and the serum concentration of free T4 were comparable in both groups of patients. A struma nodosa was more frequently found in the group of hyperthyroid patients with endocrine ophthalmopathy than in hyperthyroid patients without exophthalmus.
研究了放射性碘分次治疗伴有和不伴有内分泌性眼病的甲状腺功能亢进患者的治疗效果。为实现稳定的甲状腺功能正常代谢,与不伴有内分泌性眼病的甲状腺功能亢进患者相比,伴有内分泌性眼病的患者通常需要更多次数的治疗,放射性碘总剂量必然更高且治疗持续时间更长。两组患者的平均年龄、131I平均摄取量和游离T4血清浓度相当。结节性甲状腺肿在伴有内分泌性眼病的甲状腺功能亢进患者组中比无眼球突出的甲状腺功能亢进患者组中更常见。