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辅助性西米普利单抗在高危皮肤鳞状细胞癌中的作用

Impact of Adjuvant Cemiplimab in High-Risk Cutaneous Squamous Cell Carcinoma.

作者信息

Lim Annette M, Porceddu Sandro, Rischin Danny

机构信息

Department of Medical Oncology, Peter MacCallum Cancer Centre, 3000 Melbourne, Australia.

Sir Peter MacCallum Department of Oncology, University of Melbourne, 3000 Melbourne, Australia.

出版信息

Curr Oncol. 2025 Aug 15;32(8):459. doi: 10.3390/curroncol32080459.

Abstract

Despite cutaneous squamous cell carcinoma (CSCC) being the second most common skin cancer worldwide, there were no approved systemic therapies for patients with unresectable and/or metastatic disease prior to the advent of anti-programmed cell death protein-1 (anti-PD1) agents cemiplimab and pembrolizumab [...].

摘要

尽管皮肤鳞状细胞癌(CSCC)是全球第二常见的皮肤癌,但在抗程序性细胞死亡蛋白1(抗PD1)药物西米普利单抗和帕博利珠单抗出现之前,对于不可切除和/或转移性疾病患者,尚无获批的全身治疗方法[……]

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