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拇趾籽骨不愈合:当前证据的全面系统评价

Hallux Sesamoid Nonunion: A Comprehensive Systematic Review of Current Evidence.

作者信息

Artioli Elena, Mazzotti Antonio, Di Paola Gianmarco, Sgubbi Federico, Gemini Gianmarco, Zielli Simone Ottavio, Faldini Cesare

机构信息

IRCCS Istituto Ortopedico Rizzoli, Via Giulio Cesare Pupilli 1, 40136 Bologna, Italy.

Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum University of Bologna, 40123 Bologna, Italy.

出版信息

J Pers Med. 2025 Aug 1;15(8):342. doi: 10.3390/jpm15080342.

Abstract

The optimal management of hallux sesamoid fracture nonunions remains a subject of ongoing debate, particularly in the context of personalized medicine. This systematic review aimed to synthesize current evidence regarding surgical strategies for this rare but disabling condition. A comprehensive literature search was conducted in accordance with the PRISMA guidelines. Six studies met the inclusion criteria, encompassing a total of 80 patients. Surgical techniques varied and included open and arthroscopic sesamoidectomy, autologous bone grafting (alone or combined with screw fixation), and percutaneous screw fixation. When reported, outcomes were generally favorable, with union rates ranging from 90.5% to 100% and with consistent postoperative improvements in clinical function. Complication and reoperation rates were both 6.5%. The most frequent reoperation was sesamoidectomy for persistent pain or nonunion, followed by hardware removal. Despite the limited and low-quality evidence, available data suggest that individualized surgical planning can lead to favorable outcomes with low complication rates. Sesamoidectomy remains the most reliable salvage procedure in refractory cases. These findings support a personalized, stepwise approach to treatment-prioritizing sesamoid preservation, when feasible, while reserving excision for symptomatic nonunions. Further studies are needed to validate tailored algorithms and refine patient-specific decision-making in this challenging clinical scenario.

摘要

拇籽骨骨折不愈合的最佳治疗方法仍是一个持续争论的话题,尤其是在个性化医疗的背景下。本系统评价旨在综合有关这种罕见但致残性疾病手术策略的现有证据。按照PRISMA指南进行了全面的文献检索。六项研究符合纳入标准,共纳入80例患者。手术技术各不相同,包括开放性和关节镜下籽骨切除术、自体骨移植(单独或与螺钉固定联合)以及经皮螺钉固定。报告的结果总体良好,愈合率在90.5%至100%之间,临床功能术后持续改善。并发症发生率和再次手术率均为6.5%。最常见的再次手术是因持续性疼痛或骨折不愈合而进行的籽骨切除术,其次是取出内固定物。尽管证据有限且质量不高,但现有数据表明,个体化手术规划可带来良好的结果,并发症发生率低。在难治性病例中,籽骨切除术仍然是最可靠的挽救手术。这些发现支持采用个性化、逐步的治疗方法——在可行的情况下优先保留籽骨,同时对有症状的骨折不愈合进行切除。需要进一步研究来验证定制算法,并在这种具有挑战性的临床情况下完善针对患者的决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75f5/12387510/859df4c8ea78/jpm-15-00342-g001.jpg

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