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临床药师在资源匮乏地区医院入院用药核对中的作用

The Role of the Clinical Pharmacist in Hospital Admission Medication Reconciliation in Low-Resource Settings.

作者信息

Kovačević Tijana, Nedinić Sonja, Barišić Vedrana, Miljković Branislava, Fazlić Emir, Vukadinović Slobodan, Kovačević Pedja

机构信息

Pharmacy Department, University Clinical Centre of the Republic of Srpska, Dvanaest Beba bb, 78000 Banja Luka, Bosnia and Herzegovina.

Faculty of Medicine, University of Banja Luka, Save Mrkalja 14, 78000 Banja Luka, Bosnia and Herzegovina.

出版信息

Pharmacy (Basel). 2025 Aug 2;13(4):107. doi: 10.3390/pharmacy13040107.

Abstract

Medication discrepancies at hospital admission are common and may lead to adverse outcomes. Medication reconciliation is a critical process for minimizing medication discrepancies and medication errors at the time of hospital admission. This study aimed to evaluate the role of clinical pharmacists in identifying pharmacotherapy-related issues upon patient admission in a low-resource setting. A prospective observational study was conducted at a university hospital between 1 March and 31 May 2023. Within 24 h of admission, a clinical pharmacist documented each patient's pre-admission medication regimen and compared it with the medication history obtained by the admitting physician. Discrepancies and pharmacotherapy problems were subsequently identified. Among 65 patients, pharmacists documented 334 medications versus 189 recorded by physicians ( < 0.01). The clinical pharmacist identified 155 discrepancies, 112 (72.26%) of which were unintentional. The most frequent type was drug omission (91.07%), followed by incorrect dosage (4.46%), incorrect dosing interval (2.68%), and medications with unknown indications (1.79%). Most discrepancies were classified as errors without harm (53.57%), while 41.07% were potentially harmful. These findings underscore the importance of integrating clinical pharmacists into the healthcare team. Their active participation during hospital admission can significantly enhance medication safety and reduce preventable adverse drug events.

摘要

住院时的用药差异很常见,可能会导致不良后果。用药核对是在住院时尽量减少用药差异和用药错误的关键过程。本研究旨在评估临床药师在资源匮乏环境下患者入院时识别药物治疗相关问题的作用。2023年3月1日至5月31日在一家大学医院进行了一项前瞻性观察研究。在入院24小时内,临床药师记录每位患者入院前的用药方案,并将其与主治医生获取的用药史进行比较。随后识别出差异和药物治疗问题。在65名患者中,药师记录了334种药物,而医生记录了189种(<0.01)。临床药师识别出155处差异,其中112处(72.26%)为无意造成。最常见的类型是漏服药物(91.07%),其次是剂量错误(4.46%)、给药间隔错误(2.68%)和适应证不明的药物(1.79%)。大多数差异被归类为无伤害的错误(53.57%),而41.07%可能有害。这些发现强调了将临床药师纳入医疗团队的重要性。他们在住院期间的积极参与可显著提高用药安全性并减少可预防的药物不良事件。

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