Guillet J L, Durand J C, Salmon R J, Mangiorakos P, Pilleron J P
J Chir (Paris). 1985 Dec;122(12):655-8.
Twenty seven patients were operated on by perineo-sacral route for anal or rectal cancer. This technique used between 1965-1982 at the Institut Curie was selected because the patients were very old and/or presented with major visceral disease, where the abdomino-perineal resection was not indicated. There was no post-operative death. The margin were free of disease in every patients. 6/27 died within the 6 post-operative months mainly from cardiovascular disease. While most patients were irradiated pre operatively perineal healing was obtained within 6 months in 18/21 cases. 5 patients died of cancer during the two years following surgery. 16/21 are NED with a follow up 1-12 years. Perineo-sacral route is a good alternative from APR in old patients with cardio-vascular disease.
27例肛管或直肠癌患者采用经会阴-骶骨途径进行手术。选择1965年至1982年在居里研究所使用的这种技术，是因为患者年龄很大和/或患有严重的内脏疾病，不适合进行腹会阴联合切除术。无术后死亡病例。每位患者的切缘均无肿瘤。27例中有6例在术后6个月内死亡，主要死于心血管疾病。虽然大多数患者术前接受了放疗，但21例中有18例在6个月内实现了会阴愈合。5例患者在术后两年内死于癌症。21例中有16例无疾病证据，随访1至12年。对于患有心血管疾病的老年患者，经会阴-骶骨途径是腹会阴联合切除术的一个很好的替代方案。
