采用高效液相色谱法测定尿液中己酮可可碱的两种主要代谢产物1-(3'-羧丙基)-3,7-二甲基黄嘌呤和1-(4'-羧丁基)-3,7-二甲基黄嘌呤。 - Suppr | 超能文献

Determination of 1-(3'-carboxypropyl)-3,7-dimethylxanthine and 1-(4'-carboxybutyl)-3,7-dimethylxanthine, two major metabolites of oxpentifylline, in urine by high-performance liquid chromatography.

作者信息

Bryce T A, Burrows J L, Jolley K W

出版信息

J Chromatogr. 1985 Nov 8;344:397-402. doi: 10.1016/s0378-4347(00)82047-2.

DOI:10.1016/s0378-4347(00)82047-2

Abstract

摘要

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Determination of 1-(3'-carboxypropyl)-3,7-dimethylxanthine and 1-(4'-carboxybutyl)-3,7-dimethylxanthine, two major metabolites of oxpentifylline, in urine by high-performance liquid chromatography.采用高效液相色谱法测定尿液中己酮可可碱的两种主要代谢产物1-(3'-羧丙基)-3,7-二甲基黄嘌呤和1-(4'-羧丁基)-3,7-二甲基黄嘌呤。

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Determination of pentoxifylline and a major metabolite, 3,7-dimethyl-1-(5'-hydroxyhexyl)xanthine, by high-performance liquid chromatography.用高效液相色谱法测定己酮可可碱及其主要代谢物3,7-二甲基-1-(5'-羟基己基)黄嘌呤

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Determination of oxpentifylline and a metabolite, 1-(5'-hydroxyhexyl)-3,7-dimethylxanthine, by gas--liquid chromatography using a nitrogen-selective detector.采用氮选择性检测器，通过气液色谱法测定己酮可可碱及其代谢物1-(5'-羟基己基)-3,7-二甲基黄嘌呤。

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Determination of pentoxifylline and its 5-hydroxy metabolite in human plasma by solid-phase extraction and high-performance liquid chromatography with ultraviolet detection.通过固相萃取和带紫外检测的高效液相色谱法测定人血浆中己酮可可碱及其5-羟基代谢物。

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引用本文的文献

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Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy.己酮可可碱。对其药效学和药代动力学特性以及治疗效果的综述。

Drugs. 1987 Jul;34(1):50-97. doi: 10.2165/00003495-198734010-00003.

2

Urinary excretion of pentoxifylline and its metabolites by standardbred mares.标准赛马母马对己酮可可碱及其代谢物的尿排泄情况。

Can J Vet Res. 1989 Apr;53(2):147-53.