von Lieven H, Hahn D
MMW Munch Med Wochenschr. 1977 Aug 26;119(34):1089-92.
15 patients with distant metastases of hypernephroid carcinoma were treated with medroxyprogesterone acetate (usually 300 mg daily by mouth). In 5 patients the metastases showed slower growth, remained stationary or regressed somewhat under this treatment. But a complete regression of metastases could not be obtained. The treatment was very well tolerated. Monitoring the transaminases and alkaline phosphatase during treatment is to be recommended.
15例肾细胞癌远处转移患者接受醋酸甲羟孕酮治疗(通常每日口服300毫克)。5例患者的转移灶在该治疗下生长减缓、保持稳定或有所消退。但转移灶未能完全消退。该治疗耐受性良好。建议在治疗期间监测转氨酶和碱性磷酸酶。