Evans William N, Acherman Ruben J, Restrepo Humberto
Children's Heart Center Nevada, 3131 La Canada Ste. 230, Las Vegas, NV, 89169, USA.
Department of Pediatrics, Division of Pediatric Cardiology, University of Nevada Las Vegas, Kirk Kerkorian School of Medicine, 2040 W. Charleston Blvd Ste. 402, Las Vegas, NV, 89109, USA.
Pediatr Cardiol. 2025 Aug 27. doi: 10.1007/s00246-025-04004-2.
We reviewed those diagnosed pre- and postnatally with interrupted inferior caval vein (IICV), emphasizing the computed tomographic (CT) findings in those without complex cardiac malformations. We identified cases of IIVC diagnosed between January 2013 and December 2024. We defined non-complex cardiac malformations as secundum atrial communications with or without catheter intervention or surgery, mild semilunar valve stenosis, or a patent ductus arteriosus with or without catheter intervention or surgery. We identified 51 cases of IIVC, of which 49 had prenatal care. Of the 49 with prenatal care, 46 (94%) were diagnosed prenatally. Of the 46 prenatally diagnosed, 5 underwent fetal demise, 1 elective termination, and 40 were live born. Of the 45 live born (5 non-prenatally and 40 prenatally diagnosed), 31 (69%) had no complex cardiac malformation. Of these 31, 10 (32%) underwent CT scanning. In our experience, we noted a high prenatal detection rate for IICV, with most having no complex cardiac malformations. Further, CT scanning in a subset of patients without complex cardiac malformations demonstrated elements of left-isomeric situs, including left-atrial appendage isomerism.
我们回顾了产前和产后诊断为下腔静脉中断(IICV)的病例,重点关注无复杂心脏畸形患者的计算机断层扫描(CT)表现。我们确定了2013年1月至2024年12月期间诊断为IIVC的病例。我们将非复杂心脏畸形定义为继发孔型房间隔交通伴或不伴导管介入或手术、轻度半月瓣狭窄,或动脉导管未闭伴或不伴导管介入或手术。我们确定了51例IIVC病例,其中49例接受了产前检查。在49例接受产前检查的病例中,46例(94%)在产前被诊断出来。在46例产前诊断的病例中,5例发生胎儿死亡,1例选择性终止妊娠,40例存活出生。在45例存活出生的病例中(5例未产前诊断,40例产前诊断),31例(69%)无复杂心脏畸形。在这31例中,10例(32%)接受了CT扫描。根据我们的经验,我们注意到IICV的产前检出率很高,大多数病例无复杂心脏畸形。此外,在一部分无复杂心脏畸形的患者中进行CT扫描显示出左位异构的特征,包括左心耳异构。