Balanescu Radu, Moga Andreea, Balanescu Laura, Untaru Mara, Caragata Ruxandra, Cimpeanu Patricia
Department of Pediatric Surgery and Orthopedics, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Pediatric Surgery Department, "Grigore Alexandrescu" Clinical Emergency Hospital for Children, 011743 Bucharest, Romania.
Children (Basel). 2025 Aug 11;12(8):1052. doi: 10.3390/children12081052.
Pediatric cholelithiasis has become increasingly diagnosed, partly due to enhanced imaging accessibility and rising obesity rates. Despite laparoscopic cholecystectomy being the standard treatment, the optimal timing for surgery remains debated, especially in complicated cases. The aim of our study is to analyze the demographic, clinical, and surgical characteristics of pediatric patients undergoing cholecystectomy and to identify the most favorable timing for surgery in terms of outcomes and complications.
A retrospective study was conducted on 101 pediatric patients who underwent cholecystectomy between 2015 and 2024 at a tertiary children's hospital. Patients were categorized based on surgical timing: elective, early (day 1-4), intermediate (day 5-14), and delayed (after day 14). Demographic data, clinical presentation, laboratory values, imaging, operative time, intraoperative findings, and postoperative complications were analyzed.
The median age was 15 years, with 64.35% female. Obesity was highly prevalent and significantly associated with choledocholithiasis and pancreatitis. Elective and delayed surgeries (after 14 days) had the shortest operative times (median: 2 h) and the lowest complication rates. Early surgeries (within 4 days) showed longer operative times and a higher incidence of intraoperative difficulties and complications. Histopathological findings did not influence clinical management, suggesting potential for selective examination.
Elective or delayed cholecystectomy after a "cool-down" period of 5-14 days provides the most favorable outcomes in pediatric patients with complicated cholelithiasis. Conservative management remains appropriate for asymptomatic cases. A standardized approach to surgical timing may reduce complications and hospital costs.
小儿胆石症的诊断越来越多,部分原因是影像检查的可及性提高和肥胖率上升。尽管腹腔镜胆囊切除术是标准治疗方法,但手术的最佳时机仍存在争议,尤其是在复杂病例中。我们研究的目的是分析接受胆囊切除术的小儿患者的人口统计学、临床和手术特征,并确定就手术结果和并发症而言最有利的手术时机。
对2015年至2024年在一家三级儿童医院接受胆囊切除术的101例小儿患者进行了回顾性研究。根据手术时机对患者进行分类:择期、早期(第1 - 4天)、中期(第5 - 14天)和延迟(第14天之后)。分析了人口统计学数据、临床表现、实验室值、影像学检查、手术时间、术中发现和术后并发症。
中位年龄为15岁,女性占64.35%。肥胖非常普遍,且与胆总管结石和胰腺炎显著相关。择期和延迟手术(14天后)的手术时间最短(中位值:2小时),并发症发生率最低。早期手术(4天内)的手术时间较长,术中困难和并发症的发生率较高。组织病理学结果不影响临床管理,提示有选择性检查的可能性。
对于患有复杂胆石症的小儿患者,在5 - 14天的“冷静期”后进行择期或延迟胆囊切除术可获得最有利的结果。对于无症状病例,保守治疗仍然合适。标准化的手术时机选择方法可能会减少并发症和医院费用。