Zarroug Mohamed, Altaf Mohammed F, Shaikh Safwaan, Tidjani Abdousabour, Bashir Omnia, Ayash Mohammad I, Abdalla Hana K, Zarroug Samah H O
School of Public Health, Yale University, New Haven, CT 06520, USA.
College of Medicine, Alfaisal University, Al Takhassousi Road, P.O. Box 50927, Riyadh 11533, Saudi Arabia.
Healthcare (Basel). 2025 Aug 18;13(16):2040. doi: 10.3390/healthcare13162040.
Postpartum depression (PPD) is a major public health issue affecting maternal well-being and infant development. This systematic review and meta-analysis aimed to determine the prevalence and risk factors of PPD among Saudi women. A systematic search of PubMed, Web of Science, ProQuest, and EBSCOHost was conducted for studies published up to 31 March 2025. Statistical analysis was performed using R software (v4.4.2) with a random effects model. Study quality was assessed using the Joanna Briggs Institute (JBI) tool. A total of 32 studies published between 2014 and 2024, including 10,975 women with a mean age of 30.38 ± 6.22 years, were analyzed. Prevalence of PPD varied based on the cutoff scores of the Edinburgh Postnatal Depression Scale (EPDS): 18% (95% CI: 10-27%) at EPDS ≥ 14, 30% (95% CI: 21-38%) at EPDS ≥ 13, 59% (95% CI: 33-85%) at EPDS ≥ 12, and 45% (95% CI: 28-62%) at EPDS ≥ 10. Across studies, 32 significant risk factors for PPD were identified. The most frequently reported included lack of social support, delivery method, young maternal age, and personal or family history of depression. In the meta-analysis, three factors showed statistically significant associations with postpartum depression: limited family support ( < 0.00001), poor spouse support ( < 0.00001), and unplanned pregnancy ( = 0.04). PPD is highly prevalent among Saudi women, with marked regional disparities. These findings highlight the need for tailored mental health strategies and region-specific interventions.
产后抑郁症(PPD)是一个影响产妇身心健康和婴儿发育的重大公共卫生问题。本系统评价和荟萃分析旨在确定沙特女性中产后抑郁症的患病率及风险因素。对截至2025年3月31日发表的研究进行了系统检索,检索数据库包括PubMed、科学网、ProQuest和EBSCOHost。使用R软件(v4.4.2)并采用随机效应模型进行统计分析。研究质量采用乔安娜·布里格斯研究所(JBI)工具进行评估。共分析了2014年至2024年期间发表的32项研究,纳入10975名女性,平均年龄为30.38±6.22岁。产后抑郁症的患病率因爱丁堡产后抑郁量表(EPDS)的临界值不同而有所差异:EPDS≥14时为18%(95%CI:10 - 27%),EPDS≥13时为30%(95%CI:21 - 38%),EPDS≥12时为59%(95%CI:33 - 85%),EPDS≥10时为45%(95%CI:28 - 62%)。在各项研究中,共确定了32个产后抑郁症的显著风险因素。最常报告的因素包括缺乏社会支持、分娩方式、产妇年龄较小以及个人或家族抑郁病史。在荟萃分析中,有三个因素与产后抑郁症存在统计学显著关联:家庭支持有限(<0.00001)、配偶支持差(<0.00001)和意外怀孕(=0.04)。产后抑郁症在沙特女性中高度流行,且存在明显的地区差异。这些发现凸显了制定针对性心理健康策略和特定地区干预措施的必要性。