Pinaud M, Cozian A, Desjars P, Lepage J Y, Auvigne J, Buzelin J M, Le Neel J C, Visset J, Souron R
J Urol (Paris). 1985;91(7):423-8.
The most acurate fluid replacement is needed for the operative management of patients with pheochromocytoma. Pulmonary capillary wedge pressure monitoring must be incorporated into routine practice for assessing left ventricular filling pressure because discrepancies between central venous pressure and left-sided filling pressure may occur, even in patients apparently free of cardiopulmonary dysfunction. The response to preoperative acute volume loading was used in 11 patients--to detect preoperatively patients in whom fluid infusion was associated with a dangerous increase in pulmonary wedge pressure without improvement in forward flow and--to provide a guide for intraoperative volume replacement. This method confirmed informations suspected from baseline pressure data in one patient: distorsion between right and left ventricular filling pressures. Furthermore it showed an unsuspected ventricular dysfunction in a second patient with normal baseline pulmonary capillary wedge pressure. Both volume and speed of operative fluid challenge were adapted to this preoperative ventricular response.
嗜铬细胞瘤患者的手术治疗需要最精确的液体补充。必须将肺毛细血管楔压监测纳入常规操作,以评估左心室充盈压,因为即使在明显没有心肺功能障碍的患者中,中心静脉压和左侧充盈压之间也可能出现差异。11例患者采用术前急性容量负荷反应——术前检测液体输注与肺楔压危险升高且前向血流无改善相关的患者——并为术中容量补充提供指导。该方法证实了一名患者从基线压力数据怀疑的信息:左右心室充盈压之间的差异。此外,它还显示了一名基线肺毛细血管楔压正常的患者存在未被怀疑的心室功能障碍。手术液体挑战的容量和速度均根据术前心室反应进行调整。