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儿童阻塞性睡眠呼吸暂停低通气综合征的多导睡眠图特征及临床表型与残余睡眠呼吸暂停的关系

Polysomnographic Profile and Clinical Phenotypes of Osa in Association with Residual Sleep Apnea in Children.

作者信息

Soršáková Alžbeta, Durdikova Anna, Durdik Peter, Sulov Jakub, Dvorska Dominika, Banovcin Peter, Jesenak Milos

机构信息

Department of Pediatrics and Adolescent Medicine, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Hospital Martin, 036 59 Martin, Slovakia.

出版信息

Life (Basel). 2025 Aug 13;15(8):1282. doi: 10.3390/life15081282.

DOI:10.3390/life15081282
PMID:40868930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12387549/
Abstract

: Residual obstructive sleep apnea (OSA) is defined as persistence of the AHI at ≥1 respiratory event per hour of sleep after otorhinolaryngology intervention in pediatric population. In terms of OSA phenotypes in children, we recognize the common, adult, and congenital phenotypes. We studied 34 pediatric patients with OSA diagnosed by standard overnight polysomnography (PSG). Based on the results, all 34 patients were indicated for adenotonsillectomy (ATE). After 3 months, patients were invited to the sleep laboratory for second control PSG. These OSA patients were divided according to clinical phenotype into two groups: common phenotype and adult phenotype. Residual OSA was diagnosed in 24 patients with a mean AHI 6.67 ± 9.17 after ATE procedure. Incidence of severe residual OSA was 17.6%; moderate residual OSA was 20.6%; mild residual OSA was 32.4%. Residual OSA in classic phenotype was present in eight patients (57.1%). In total, 16 patients with the adult phenotype of OSA (80.0%) were diagnosed with residual OSA. Prevalence was significantly higher in children with the adult phenotype ( < 0.001). We concluded that there is a higher risk of residual OSA in children with the adult phenotype. Phenotyping of children with OSA appears to be an important tool for further management and also in predicting the severity of residual OSA.

摘要

残余阻塞性睡眠呼吸暂停(OSA)被定义为儿科人群在耳鼻喉科干预后,睡眠中每小时呼吸事件指数(AHI)持续≥1次。就儿童OSA表型而言,我们认识到常见型、成人型和先天性表型。我们研究了34例经标准夜间多导睡眠图(PSG)诊断为OSA的儿科患者。根据结果,所有34例患者均被建议行腺样体扁桃体切除术(ATE)。3个月后,患者被邀请到睡眠实验室进行第二次对照PSG检查。这些OSA患者根据临床表型分为两组:常见型和成人型。24例患者在ATE手术后被诊断为残余OSA,平均AHI为6.67±9.17。重度残余OSA的发生率为17.6%;中度残余OSA为20.6%;轻度残余OSA为32.4%。经典表型中有8例(57.1%)存在残余OSA。总共有16例成人型OSA患者(80.0%)被诊断为残余OSA。成人型表型儿童的患病率显著更高(<0.001)。我们得出结论,成人型表型儿童发生残余OSA的风险更高。对OSA儿童进行表型分析似乎是进一步管理以及预测残余OSA严重程度的重要工具。

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本文引用的文献

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Cureus. 2025 Jan 27;17(1):e78051. doi: 10.7759/cureus.78051. eCollection 2025 Jan.
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High Prevalence of Obstructive Sleep-Disordered Breathing in Pediatric Patients With Turner Syndrome.特纳综合征患儿阻塞性睡眠呼吸暂停低通气综合征的高患病率。
Otolaryngol Head Neck Surg. 2024 Mar;170(3):905-912. doi: 10.1002/ohn.576. Epub 2023 Nov 8.
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Am J Respir Crit Care Med. 2024 Feb 1;209(3):248-261. doi: 10.1164/rccm.202310-1857ST.
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