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经合组织成员国促进健康老龄化和疾病预防的经济影响范围综述

A Scoping Review on the Economic Impacts of Healthy Ageing Promotion and Disease Prevention in OECD Member Countries.

作者信息

Demirtas Ezgi Dilek, Flahault Antoine

机构信息

Institute of Economic Research, Faculty of Economics and Business, University of Neuchâtel, Avenue du Premier-Mars 26, 2000 Neuchâtel, Switzerland.

Institute of Global Health, Faculty of Medicine, University of Geneva, 9 Chemin des Mines, 1202 Geneva, Switzerland.

出版信息

Int J Environ Res Public Health. 2025 Jul 22;22(8):1161. doi: 10.3390/ijerph22081161.

Abstract

The economic impact of health promotion and disease prevention interventions in ageing populations remains debated, as theories of morbidity compression and expansion offer contrasting views on the relationship between life expectancy and duration of morbidity. A MEDLINE search was conducted to identify studies evaluating the economic impact of health promotion or primary or secondary prevention interventions in OECD countries, over a lifetime time horizon. Among the 29 studies included, 16 reported cost-saving interventions (reducing costs while improving health outcomes), 11 reported cost-effective interventions (health gains at an acceptable additional cost based on an established threshold), and two presented cost-ineffective interventions (costs exceeding the threshold for the health benefits achieved). Interventions targeting diabetes and obesity prevention were cost-saving; cancer screening and fall prevention strategies were cost-effective; whereas interventions targeting rare diseases were cost-ineffective. Regulatory interventions were also cost-saving, while most programme-based interventions were cost-effective. Cost-saving or cost-effective interventions generally adopted broader analytical perspectives, while cost-ineffective ones employed narrower perspectives. The four studies that incorporated competing risks-despite using a narrower healthcare sector perspective-still found the interventions to be cost-saving or cost-effective interventions. None of the included studies assessed whether interventions led to morbidity compression or expansion. Only a few studies considered equity impact; those that did reported improved outcomes for disadvantaged groups, in regulatory and community-based interventions. Further research is needed to quantify morbidity outcomes and enhance methodological consistency, particularly with respect to analytical perspectives, the integration of competing risks, and the inclusion of equity analyses.

摘要

健康促进和疾病预防干预措施对老年人群的经济影响仍存在争议,因为发病率压缩和扩张理论对预期寿命与发病持续时间之间的关系提出了截然不同的观点。我们进行了一项MEDLINE检索,以确定在整个生命周期内评估经合组织国家健康促进或一级或二级预防干预措施经济影响的研究。在纳入的29项研究中,16项报告了成本节约型干预措施(在改善健康结果的同时降低成本),11项报告了成本效益型干预措施(基于既定阈值,以可接受的额外成本获得健康收益),两项报告了成本无效型干预措施(成本超过所实现健康效益的阈值)。针对糖尿病和肥胖预防的干预措施具有成本节约效果;癌症筛查和跌倒预防策略具有成本效益;而针对罕见病的干预措施则成本无效。监管干预措施也具有成本节约效果,而大多数基于项目的干预措施具有成本效益。成本节约型或成本效益型干预措施通常采用更广泛的分析视角,而成本无效型干预措施则采用更狭窄的视角。纳入的四项考虑了竞争风险的研究——尽管采用了更狭窄的医疗保健部门视角——仍然发现这些干预措施是成本节约型或成本效益型干预措施。纳入的研究均未评估干预措施是否导致发病率压缩或扩张。只有少数研究考虑了公平影响;那些考虑了公平影响的研究报告称,在监管和基于社区的干预措施中,弱势群体的结果有所改善。需要进一步开展研究,以量化发病结果并提高方法的一致性,特别是在分析视角、竞争风险的整合以及公平分析的纳入方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71ca/12385553/2788c428f29c/ijerph-22-01161-g001.jpg

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