南非一家公立基层医疗诊所中抗结核治疗不依从性的决定因素：提高长期护理质量
Determinants of Non-Adherence to Anti-Tuberculosis Treatment in a Public Primary Healthcare Clinic in South Africa: Improving the Quality of Long-Term Care.
作者信息
Katende-Kyenda Lucky Norah
机构信息
Department of Internal Medicine and Pharmacology, Faculty of Medicine and Health Sciences, Walter Sisulu University, Sissons Street, Fortgale, Mthatha 5117, Eastern Cape, South Africa.
出版信息
Int J Environ Res Public Health. 2025 Jul 31;22(8):1209. doi: 10.3390/ijerph22081209.
BACKGROUND
Non-adherence to anti-tuberculosis treatment remains a major obstacle to increasing tuberculosis treatment success rates and enhancing healthcare expenditure. The aim of this study was to identify determinants contributing to non-adherence to anti-tuberculosis treatment in a public primary healthcare clinic in South Africa.
METHOD
A cross-sectional study was carried out to collect data from 65 participants using face-to-face interviews with a structured questionnaire. Data were analyzed using SPSS.
RESULTS
Of the 65 participants interviewed, 41 (63.08%) were males and 24 (36.92%) were females. A total of 45 (69.23%) were adherents and 20 (30.77%) were non-adherents. Gender was the major predictor of non-adherence with more males committed to treatment than females with a significant association (X = 65.00 and of <0.001).
CONCLUSIONS
The major contributing factors to non-adherence were long dis-tances to the clinics, a lack of family support, and unemployment. Comprehensive programs addressing these multifactorial factors are needed for successful treatment and eradication of tuberculosis.
背景
不坚持抗结核治疗仍然是提高结核病治疗成功率和增加医疗保健支出的主要障碍。本研究的目的是确定南非一家公立基层医疗诊所中导致不坚持抗结核治疗的决定因素。
方法
采用横断面研究，通过面对面访谈和结构化问卷从65名参与者中收集数据。使用SPSS分析数据。
结果
在接受访谈的65名参与者中，41名（63.08%）为男性，24名（36.92%）为女性。共有45名（69.23%）坚持治疗，20名（30.77%）不坚持治疗。性别是不坚持治疗的主要预测因素，男性坚持治疗的人数多于女性，差异有统计学意义（X = 65.00，P < 0.001）。
结论
不坚持治疗的主要促成因素是到诊所的距离远、缺乏家庭支持和失业。需要制定全面的计划来解决这些多因素问题，以成功治疗和根除结核病。
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