Genome-Wide Identification Analysis of the Gene Family in and Its Expression Analysis in .

: RAB11 (RABA) is a type of RAB GTPase. RAB GTPases are key components of membrane trafficking mechanisms, Rab11 is implicated in a variety of biological developmental processes and responses to biotic and abiotic stresses. Nevertheless, the role of Rab11 in the defense mechanisms of cotton against () remains to be elucidated. : In the present study, by analyzing the transcriptome data of () infected with , in combination with gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses, the research focused on endocytosis. Further, through bioinformatics approaches, the endocytosis-related gene was identified. We conducted a genome-wide identification and analysis of in . In addition, by integrating transcription factor (TF) prediction, prediction of protein-protein interactions (PPI) and quantitative real-time polymerase chain reaction (qRT-PCR), the gene expression of at different infection periods of (0, 24 and 72 hpi) were analyzed and validated. : The analysis of transcriptome data revealed that the endocytosis pathway is implicated in the stress response of cotton to . Additionally, three genes were identified as being involved in this stress response. Phylogenetic analysis revealed that the 65 genes in the family could be divided into four subgroups, each with similar gene structures and conserved motif patterns. : The downregulation of in is closely linked to its defense against . TF prediction coupled with PPI offers a roadmap for dissecting the signaling pathways, functional validation, and network construction of the three genes.