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一只金毛猎犬疑似因颈内动脉夹层导致霍纳综合征。

Horner Syndrome Secondary to Suspected Internal Carotid Artery Dissection in a Golden Retriever.

作者信息

Davini Tommaso, Remelli Carlotta, Mattei Chiara, Specchi Swan, Biserni Roberta, Bernardini Marco

机构信息

Anicura "Ospedale Veterinario I Portoni Rossi", Zola Predosa, Bologna, Italy.

Antech Imaging Service, Fountain Valley, California, USA.

出版信息

J Vet Intern Med. 2025 Sep-Oct;39(5):e70216. doi: 10.1111/jvim.70216.

DOI:10.1111/jvim.70216
PMID:40873263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12391725/
Abstract

A 5-year-old male golden retriever was presented after a subacute onset of left-sided Horner syndrome (HS). The dog had anisocoria with left-sided miosis, ptosis of the upper eyelid, and third eyelid protrusion in the left eye. Because of the absence of additional neurological abnormalities, clinical signs were suggestive of left isolated HS, and the lesion was localized at the level of either the preganglionic or postganglionic neuron of the sympathetic chain. Magnetic resonance imaging (MRI) of the head and total body computed tomography (CT) identified marked narrowing and irregularity of the left internal carotid artery (ICA) in addition to loss of normal vessel flow-void and T1-weighted hyperintensity in the lumen of the left ICA. Except for these abnormalities, MRI and CT results were normal. These findings were suggestive of left internal carotid artery dissection (ICAD), suggesting that ICAD should be considered as a possible differential diagnosis of HS in dogs.

摘要

一只5岁雄性金毛猎犬在出现左侧霍纳综合征(HS)亚急性发作后前来就诊。该犬存在瞳孔不等大,左侧瞳孔缩小、上眼睑下垂以及左眼第三眼睑突出。由于未发现其他神经功能异常,临床症状提示为左侧孤立性HS,病变定位于交感神经链的节前或节后神经元水平。头部磁共振成像(MRI)和全身计算机断层扫描(CT)显示,除左侧颈内动脉(ICA)正常血管流空消失和T1加权高信号外,左侧ICA明显狭窄且不规则。除这些异常外,MRI和CT结果均正常。这些发现提示左侧颈内动脉夹层(ICAD),表明ICAD应被视为犬HS的一种可能鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e2e/12391725/7fbb5a5d5249/JVIM-39-e70216-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e2e/12391725/da29d023dce1/JVIM-39-e70216-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e2e/12391725/372829939bc8/JVIM-39-e70216-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e2e/12391725/7fbb5a5d5249/JVIM-39-e70216-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e2e/12391725/da29d023dce1/JVIM-39-e70216-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e2e/12391725/372829939bc8/JVIM-39-e70216-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e2e/12391725/7fbb5a5d5249/JVIM-39-e70216-g003.jpg

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本文引用的文献

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Vet Comp Oncol. 2025 Mar;23(1):37-41. doi: 10.1111/vco.13023. Epub 2024 Nov 4.
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Cervical Artery Dissections: Etiopathogenesis and Management.颈动脉夹层:病因发病机制与治疗管理。
Vasc Health Risk Manag. 2022 Sep 2;18:685-700. doi: 10.2147/VHRM.S362844. eCollection 2022.
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The diagnostic yield of advanced imaging in dogs with Horner's syndrome presenting with and without additional clinical signs: A retrospective study of 120 cases (2000-2018).伴有和不伴有其他临床症状的霍纳氏综合征犬进行高级影像学检查的诊断效果:120 例(2000-2018 年)回顾性研究。
Vet Ophthalmol. 2022 May;25 Suppl 1:51-59. doi: 10.1111/vop.12918. Epub 2021 Jul 7.
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Establishment of Carotid Artery Dissection and MRI Findings in a Swine Model.猪模型中颈动脉夹层的建立及磁共振成像表现
Front Neurol. 2021 Jun 16;12:669276. doi: 10.3389/fneur.2021.669276. eCollection 2021.
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A review of Horner's syndrome in small animals.小动物霍纳综合征综述。
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ACS Chem Neurosci. 2018 Feb 21;9(2):177-186. doi: 10.1021/acschemneuro.7b00405. Epub 2017 Dec 20.
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The Yield of Diagnostic Imaging in Patients with Isolated Horner Syndrome.孤立性霍纳综合征患者的诊断性影像学检查结果
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