Liu Tingting, Lv Jing, Xu Luxiang, Zhang Xiaomei, Xiao Qing, Li Jun, Zhang Zhaoli, Liu Yao
Chongqing Key Laboratory for the Mechanism and Intervention of Cancer Metastasis, Department of Hematology-Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Chongqing Key Laboratory for the Mechanism and Intervention of Cancer Metastasis, Nursing Department, Chongqing University Cancer Hospital, Chongqing, China.
Front Nutr. 2025 Aug 12;12:1623692. doi: 10.3389/fnut.2025.1623692. eCollection 2025.
To explore the effect of nursing scheme based on efficacy theory combined with nutritional intervention on patients with multiple myeloma (MM) complicated with renal failure.
Ninety-two patients with MM complicated with renal failure in our hospital from April 2022 to April 2024 were randomly divided into control group (46 cases, using conventional nursing) and observation group (46 cases, using nursing scheme based on efficacy theory combined with nutritional intervention). The CDSES score of self-efficacy, CD-RISC score of resilience, CFS score of cancer-related fatigue, nutrition related indicators (ALB, Hb, PA) and FLIC score of quality of life were compared between the two groups.
After the intervention, both groups showed increased CDSES and CD-RISC scores, with the observation group significantly higher than controls. And the levels of ALB, Hb and PA in the observation group were significantly higher than those in the control group. Cancer fatigue scale (CFS) scores at T1, T2, and T3 were reduced from baseline (T0) in both groups; and the observation group was significantly lower than the control group. After the intervention, the scores of the four dimensions of good body and ability, good psychology, difficulties caused by cancer and good society of the two groups were significantly improved, and the scores of the observation group were higher than those of the control group; The scores of nausea dimension in the two groups were significantly lower than those before the intervention, and the control group decreased more than the observation group ( < 0.05).
The efficacy theory-based nursing plan combined with nutritional intervention benefits MM patients with renal failure. It improves self-efficacy and psychological resilience, reduces cancer-related fatigue, and enhances nutritional status and overall quality of life.
探讨基于效能理论的护理方案联合营养干预对多发性骨髓瘤(MM)合并肾衰竭患者的影响。
选取2022年4月至2024年4月在我院就诊的92例MM合并肾衰竭患者,随机分为对照组(46例,采用常规护理)和观察组(46例,采用基于效能理论的护理方案联合营养干预)。比较两组患者的自我效能感CDSES评分、心理弹性CD-RISC评分、癌因性疲乏CFS评分、营养相关指标(白蛋白、血红蛋白、前白蛋白)及生活质量FLIC评分。
干预后,两组患者的CDSES评分和CD-RISC评分均升高,观察组显著高于对照组。观察组白蛋白、血红蛋白和前白蛋白水平显著高于对照组。两组在T1、T2和T3时的癌因性疲乏量表(CFS)评分均较基线(T0)降低,且观察组显著低于对照组。干预后,两组患者在身体与能力良好、心理良好、癌症所致困难及社会良好四个维度的评分均显著提高,且观察组高于对照组;两组恶心维度评分均显著低于干预前,且对照组下降幅度大于观察组(P<0.05)。
基于效能理论的护理方案联合营养干预对MM合并肾衰竭患者有益,可提高自我效能感和心理弹性,减轻癌因性疲乏,改善营养状况和整体生活质量。